Results 41 to 50 of about 1,501,833 (160)

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama, Bibiana Kazaura, Theresia E. Lutufyo, Baraka E. Mrisho, Hery O. Kimwela, Marco E. Nyakasalule, Ronald M. Costantini, Eliya Msemwa, Florence Malamso, George Assenga, Julius Kinyange, Josephine R. Laswai, Fabian M. Kamana, Godfery Malangwa, David S. Mazengo, Raymond Leiya, Andrea S. Hondo, Masuma Gulamhussein, Happiness J. Mathew, Paul P. Mwasapi, Phillip S. Muhochi, Hakolo L. Mgaya, Moa E. Kalunga, Brendan P. Shayo, Amani E. Senso, Leonia N. Ndakamaze, Tuzo Lyuu, Anna A. Sanga, Rosemary P. Minja, Deusdedit Ndilanha, Emmanuel J. Magandi, Nkulikiye Kanani, Anthony J. Gyunda, Immaculate R. Goima, Justus L. Ishengoma, Janet L. Mtenga, Flora N. Ndobho, Kigocha L. Okengo, Paschal N. Kulwijila, Pius C. Njingo   +39 more
wiley   +1 more source

Short-term tocolytics for preterm delivery – current perspectives

International Journal of Women's Health, 2014
David M Haas, Tara Benjamin, Renata Sawyer, Sara K QuinneyDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, USAAbstract: Administration of short-term tocolytic agents can prolong pregnancy for women in ...
Haas DM, Benjamin T, Sawyer R, Quinney SK   +3 more
doaj  

Priming of labor with tafoxiparin in nulliparous term pregnant women with unripe cervix—Proof‐of‐concept and dose‐finding results from a randomized controlled trial

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1566-1577, August 2026.
This study shows that tafoxiparin 300 mg can increase the rate of cervical ripening and the likelihood of spontaneous onset of labor, while also reducing the duration of labor in women achieving spontaneous onset of labor. The favorable safety profile of tafoxiparin suggests suitability for routine clinical use, including home administration.
Gunvor Ekman‐Ordeberg, Maria Jonsson, Marie Blomberg, Malin Melin, Ylva Stjernholm‐Vladic, Sebastian B. Gidlöf, Dag Wide‐Swensson, Kati Tihtonen, Inge C. Olsen, Lena Degling‐Wikingsson, Per Blom, Leena Rahkonen   +11 more
wiley   +1 more source

Preterm labor:current tocolytic options for the treatment of preterm labor

, 2014
While tocolytic therapy may not be indicated in all cases of spontaneous preterm labor (SPTL), the evidence that they are superior to placebo is robust.
Jørgensen, Jan Stener, Weile, Louise Katrine Kjær, Lamont, Ronald Francis   +2 more
core   +1 more source

In vitro comparison of four tocolytic agents, alone and in combination

, 1994
Objective: To compare the tocolytic effects or magnesium sulfate, ritodrine, terbutaline, and nifedipine on human myometrial strips. Methods: Myometrial strips were suspended in organ chambers for isotonic measurements and contracted with KCl.
Belfort M.A., Saade G.R., Erturan B., Moise K.J., Taskin O., Jr.   +5 more
core   +1 more source

Structure–Activity Relationship Study on Ligands Activating the Voltage‐Gated Potassium Channel KV7.1

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Activation of the voltage gated K+ channel KV7.1 leads to hyperpolarization shift of cell membranes. In a thorough SAR study eight positions of the lead compound (R)‐L3 were modified. (R)‐configuration, the indolylmethyl moiety in 3‐position and the 2‐fluorophenyl moiety in 5‐position appeared to be essential for high KV7.1 activation, whereas an OH ...
Florian Roßner, Judith Schmidt, Guiscard Seebohm, Bernhard Wünsch   +3 more
wiley   +1 more source

A historical narrative review through the field of tocolysis in threatened preterm birth

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Preterm birth presents a significant challenge in clinical obstetrics, requiring effective strategies to reduce associated mortality and morbidity risks.
Tijn van Winden, Carolien Roos, Ben W. Mol, E. Pajkrt, Martijn A. Oudijk   +4 more
doaj   +1 more source

A Comparative Study to Determine the Efficacy of Atosiban versus Nifedipine in Management of Preterm Labour [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Preterm Labour (PTL) remains a significant challenge in obstetrics, contributing to neonatal morbidity and mortality. The management of PTL involves the use of tocolytic agents to delay delivery, thereby allowing for further foetal ...
Vidya Gaikwad, Jay Patel, Suhas Gaikwad
doaj   +1 more source

In the gravid human uterus, oxytocin induces smooth muscle cell contraction via transient receptor potential vanilloid 4 channel activation

The Journal of Physiology, Volume 604, Issue 7, Page 3135-3158, 1 April 2026.
Abstract figure legend In gravid human uterus smooth muscle, the oxytocin receptor (OXTR) and transient receptor potential vanilloid 4 (TRPV4) calcium channel colocalize at <40 nm by proximity ligation. TRPV4 is necessary for oxytocin‐induced calcium influx and contractility in uterine smooth muscle cells.
Daiana Fornes, Jessica R. Ansari, Guillermina Michel, Cristina M. Alvira, David N. Cornfield   +4 more
wiley   +1 more source

Tocolytic therapy in threatened preterm labor [PDF]

, 1970
Summary The most important benefit of tocolysis is a 48-hour prolongation of gestational age in order to administer corticosteroids to reduce perinatal mortality and morbidity, as well as, if necessary, to gain time for “in utero” transfer to a tertiary ...
Leszczyńska-Gorzelak, Bożena, Marciniak, Beata, Bartosiewicz, Jacek, Oleszczuk, Jan, Kimber-Trojnar, Żaneta   +4 more
core