Indomethacin Inhibits Cancer Cell Migration via Attenuation of Cellular Calcium Mobilization
Molecules, 2013 Non-steroidal anti-inflammatory drugs (NSAIDs) were shown to reduce the risk of colorectal cancer recurrence and are widely used to modulate inflammatory responses. Indomethacin is an NSAID.
Ke-Li Tsai +10 more
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ORAL N-ACETYL CYSTEINE VERSUS RECTAL INDOMETHACIN FOR PREVENTION OF POST ERCP PANCREATITIS: A MULTICENTER MULTINATIONAL RANDOMIZED CONTROLLED TRIAL [PDF]
Arquivos de Gastroenterologia, 2022 Background This multicenter multinational RCT designed to compare the efficacy of suppository indomethacin and NAC for prevention of PEP. Methods: During a 6-month period, all of the ERCP cases in seven referral centers were randomly assigned to ...
Pezhman ALAVINEJAD +19 more
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Role of vitamin C and rectal indomethacin in preventing and alleviating post-endoscopic retrograde cholangiopancreatography pancreatitis: a clinical study [PDF]
Clinical Endoscopy, 2023 Background/Aims This study aimed to determine whether vitamin C in addition to indomethacin decreases the occurrence and severity of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) occurrence and severity.
Amir Sadeghi +4 more
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Journal of Pharmaceutical Analysis, 2021 Alpinia officinarum Hance of the Chinese traditional herb for the treatment of emesis, abdominal pain and diarrhea has been used to counteract gastric disease induced by indomethacin in rats without obvious side effects.
Xuguang Zhang +7 more
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iScience, 2023 Summary: Severe infections with coronaviruses are often accompanied with hyperinflammation, requiring therapeutic strategies to simultaneously tackle the virus and inflammation.
Yining Wang +9 more
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Potential Protective Effects of Sildenafil and Moringa on Experimentally-induced Gastric Ulcer in Rats [PDF]
Egyptian Journal of Cancer and Biomedical Research, 2020 BACKGROUND: Sildenafil and Moringa appear to have the ability to reduce the ulcerogenic effect of the drugs used to induce ulcers in rats. AIM: The present study was conducted to investigate the gastroprotective effects of sildenafil citrate, Moringa ...
Raghda El Mahdy +3 more
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Synthesis of enhanced lipid solubility of indomethacin derivatives for topical formulations
Heterocyclic Communications, 2022 Indomethacin is a nonselective nonsteroidal anti-inflammatory drug with serious side effects such as depression, hallucination, and gastrointestinal irritation. This study aims to enhance indomethacin lipid solubility of indomethacin derivative to use it
Abualhasan Murad +4 more
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Biomolecules, 2023 Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action mechanism, COX-independent ways are associated with beneficial effects in cancer.
Neudo Buelvas +9 more
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Effect of Quercetin on Injury to Indomethacin-Treated Human Embryonic Kidney 293 Cells
Life, 2021 Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat inflammation and pain and even to prevent the progression of cardiovascular disease. They have become widely used because of their effectiveness, especially among athletes performing high ...
Chun Chen +4 more
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ANTIULCER ACTIVITY OF PLACENTAL CRYOEXTRACT IN EXPERIMENTAL INDOMETHACIN-INDUCED ULCEROGENESIS
Acta Medica Leopoliensia, 2021 Aim. The side effects associated with the use of indometacin are noted by about 30-60% of patients, therefore, in this context the problem of adverse event rate reduction is still relevant today.
Fedir Hladkykh
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