Results 31 to 40 of about 46,561 (203)

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

Chemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato, Philipp Natho, Marco Colella, Renzo Luisi   +3 more
wiley   +1 more source

Paranoid psychosis after a single parenteral dose of indomethacin administered for headache diagnosis: A case and review of the literature

Cephalalgia Reports
Background: Indomethacin is a non-steroidal anti-inflammatory used to diagnose and treat hemicrania continua and paroxysmal hemicrania. Treatment can be complicated by gastrointestinal adverse effects; less commonly reported are idiosyncratic ...
Nazia Karsan, Ray Pyari Bose, Peter J Goadsby   +2 more
doaj   +1 more source

Preparation of Prodrug from Indomethacine and Ascorbic acid and study of It's Effect on Asparatate amino transferase Enzyme Partially Purified from Blood of Diabetic Patients Type two. [PDF]

Kirkuk Journal of Science, 2016
The aim of this study is to prepare a new ester prodrug. used for this purpose ascorbic acid vitamin C and indomethacin by esterification reaction, and partial purification of the AST from blood serum with diabetes type II, and we following steps: 1 ...
Amina F. Yahya, Hanaa K. Salih, Firas T. Maher   +2 more
doaj   +1 more source

Nitrooxylation in Organic Synthesis: From Classical Nitrate Ester Formation to Modern Catalytic Strategies

Chemistry – A European Journal, EarlyView.
Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley   +1 more source

Effect of Aspirin and Indomethacin on Prostaglandin E2 Synthesis in C6 Glioma Cells

Kaohsiung Journal of Medical Sciences, 2004
Prostaglandin E2 (PGE2) plays an important role in immunosuppression and tumor growth. PGE2 inhibitors such as aspirin and indomethacin suppress experimental tumor growth. Little is known of the relationship between PGE2 synthesis in brain tumors and the
Shiuh-Lin Hwang, Kung-Shing Lee, Chih-Lung Lin, Ann-Shung Lieu, Chi-Yun Cheng, Joon-Khim Loh, Yan-Fen Hwang, Yu-Feng Su, Shen-Long Howng   +8 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats [Retraction]

International Journal of Nanomedicine, 2023
Ahmed OAA, Fahmy UA, Bakhaidar R, et al. Int J Nanomedicine. 2020;15:2529–2539. The Editor and Publisher of International Journal of Nanomedicine are retracting the above published article. An investigation by the Publisher found overlap in images
Ahmed OAA, Fahmy UA, Bakhaidar R, El-Moselhy MA, Alfaleh MA, Ahmed ASF, Hammad ASA, Aldawsari H, Alhakamy NA   +8 more
doaj  

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source

Gastroprotective activity of Jervine alkaloid from Veratrum album on gastric ulcer in rat

Heliyon
Aim: In this study, we investigated how Jervine affected gastric tissue in rats following the development of indomethacin-induced ulcers. Methods: Jervine (JER) 200 mg/kg and JER 400 mg/kg were given orally to the experimental groups 12h after the fasten
Serdar Yigit, Tuba Aydin, Nilnur Eyerci, Muhammed Yayla, Lale Duysak, Fatma Necmiye Kaci, Erdem Toktay, Arzu Gezer, Seyit Ali Bingol   +8 more
doaj   +1 more source

The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares, Jacy Bezerra Parmera, Pedro Augusto Sampaio Rocha‐Filho   +2 more
wiley   +1 more source