Results 31 to 40 of about 68,039 (253)

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

open access: yesAdvanced Science, EarlyView.
Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang   +2 more
wiley   +1 more source

Influence of adrenalectomy on protective effects of urocortin I, a corticotropin-releasing factor (CRF)-related peptide, against indomethacin-induced enteropathy in rats

open access: yesИнтегративная физиология, 2020
The influence of adrenalectomy on indomethacin-induced enteropathy in rats was examined and the possible involvement of adrenal glucocorticoids in protective effects of urocortin I, a CRF agonist, was investigated.
Koji Takeuchi
doaj   +1 more source

Bovine colostrum is a health food supplement which prevents NSAID induced gut damage [PDF]

open access: yes, 1999
BACKGROUNDNon-steroidal anti-inflammatory drugs (NSAIDs) are effective for arthritis but cause gastrointestinal injury. Bovine colostrum is a rich source of growth factors and is marketed as a health food supplement.AIMSTo examine whether spray dried ...
R A Goodlad   +15 more
core   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Dissolution Studies of Physical Mixtures of Indomethacin with Alpha- and Gamma-Cyclodextrins

open access: yesBiomolecules & Biomedicine, 2010
Oral administration of indomethacin has been limited by its poor water solubility. Cyclodextrins have been recognized as potential candidates to overcome the poor solubility of indomethacin through the formation of inclusion complexes.
Edina Vranić, Alija Uzunović
doaj   +1 more source

Indomethacin Affects the Inflammatory Response via Interaction with the RhoA-Actin Cytoskeleton in THP-1 Cells

open access: yesExperimed, 2023
Objective: Inflammation is a complex reaction present in numerous disorders. Indomethacin, a compound possessing an indoline core, is a Nonsteroidal Anti-Inflammatory Drug (NSAID) that is commonly prescribed for inflammation and pain.
Ebru Hacıosmanoğlu Aldoğan   +5 more
doaj   +1 more source

Gastroprotective effects of both aqueous and ethanolic extracts of Lemon verbena leaves against indomethacin-induced gastric ulcer in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Regarding Lemon verbena gastroprotective effects, we investigated the protective effects of Lemon verbena extracts on reducing gastric ulcer induced by indomethacin.Materials and Methods: Rats received aqueous and ethanolic extracts of ...
Habibeh Mashayekhi-sardoo   +4 more
doaj   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

open access: yesAdvanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu   +11 more
wiley   +1 more source

The Clinical Significance of Indomethacin-Probenicid Interaction [PDF]

open access: yes, 1974
The effect of the addition of probenecid to oral and rectal regimes of indomethacin was studied in three groups of rheumatoid arthritic patients. The addition of probenecid increases plasma levels of indomethacin given both orally and rectally and ...
Dick, W. C.   +4 more
core   +1 more source

The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice

open access: yes, 2020
Objective: Butein is a potential agent first isolated from Rhus verniciflua that has medicinal value in East Asia and has been used in the treatment of gastritis, gastric cancer, and atherosclerosis since ancient times.
Rustem Anil Ugan   +3 more
core   +1 more source

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