Results 41 to 50 of about 68,039 (253)

OnabotulinumtoxinA for Hemicrania Continua: open label experience in 9 patients. [PDF]

open access: yes, 2015
Hemicrania continua is a strictly unilateral, continuous headache, typically mild to moderate in severity, with severe exacerbations commonly accompanied by cranial autonomic features and migrainous symptoms. It is exquisitely responsive to Indomethacin.
Lagrata, S   +11 more
core   +3 more sources

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

open access: yesAdvanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia   +13 more
wiley   +1 more source

New use of indomethacin [PDF]

open access: yes, 2014
Indomethacin in ground pellet mixture was fed to a group of starved albino mice 6-8 weeks old, weighing 20-26 g in varying concentrations ranging from 0.0125–1.0 % w/w.
Maitai, CK, Munenge, RW
core   +1 more source

Antioxidant effects of betaine against Indomethacin-induced gastric damage in rats

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
Introduction: Betaine (trimethyl glycine) is known as methyl group donor and antioxidant in previous reports. The aim of this study was to assess the antioxidant effects of betaine in Indomethacin-induced gastric damages.
M Alirezaei   +3 more
doaj  

NSAID targets SIRT3 to trigger mitochondrial dysfunction and gastric cancer cell death

open access: yesiScience
Summary: Gastric cancer (GC) is a deadly malignancy that demands effective therapeutic intervention capitalizing unique drug target/s. Here, we report that indomethacin, a cyclooxygenase non-selective non-steroidal anti-inflammatory drug, arrests GC cell
Subhashis Debsharma   +12 more
doaj   +1 more source

Probing amorphous and crystalline pharmaceuticals systems using NMR [PDF]

open access: yes, 2006
The Ή and '3C solution-state NMR spectra of the three studied drug molecules (indomethacin, nifedipine and carbamazepine) were fully assigned. This led to the characterisation and assignment of the '3C CPMAS SSNMR spectra of the stable polymorphic forms ...
Foumier, Romain
core  

S‐allyl‐L‐cysteine protects hepatocytes from indomethacin‐induced apoptosis by attenuating endoplasmic reticulum stress

open access: yesFEBS Open Bio, 2020
Drug‐induced liver injury (DILI) can lead to acute liver failure, a lethal condition which may require liver transplantation. Hepatotoxicity associated with nonsteroidal anti‐inflammatory drugs (NSAIDs) accounts for ~ 10% of all DILI.
Peng Chen   +6 more
doaj   +1 more source

Effect of Aspirin and Indomethacin on Prostaglandin E2 Synthesis in C6 Glioma Cells

open access: yesKaohsiung Journal of Medical Sciences, 2004
Prostaglandin E2 (PGE2) plays an important role in immunosuppression and tumor growth. PGE2 inhibitors such as aspirin and indomethacin suppress experimental tumor growth. Little is known of the relationship between PGE2 synthesis in brain tumors and the
Shiuh-Lin Hwang   +8 more
doaj   +1 more source

Paranoid psychosis after a single parenteral dose of indomethacin administered for headache diagnosis: A case and review of the literature

open access: yesCephalalgia Reports
Background: Indomethacin is a non-steroidal anti-inflammatory used to diagnose and treat hemicrania continua and paroxysmal hemicrania. Treatment can be complicated by gastrointestinal adverse effects; less commonly reported are idiosyncratic ...
Nazia Karsan   +2 more
doaj   +1 more source

Preparation of Prodrug from Indomethacine and Ascorbic acid and study of It's Effect on Asparatate amino transferase Enzyme Partially Purified from Blood of Diabetic Patients Type two. [PDF]

open access: yesKirkuk Journal of Science, 2016
The aim of this study is to prepare a new ester prodrug. used for this purpose ascorbic acid vitamin C and indomethacin by esterification reaction, and partial purification of the AST from blood serum with diabetes type II, and we following steps: 1 ...
Amina F. Yahya   +2 more
doaj   +1 more source

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