Results 41 to 50 of about 46,561 (203)
Differential renal adverse effects of ibuprofen and indomethacin in preterm infants: a review
Clinical Pharmacology: Advances and Applications, 2014 Gian Maria Pacifici Medical School, Department of Translational Research and New Technologies in Medicine and Surgery, Section of Pharmacology, University of Pisa, Pisa, Italy Objective: The objective of this study was to evaluate the extent of renal ...
Pacifici GM
doaj
Разработка и регистрация лекарственных средствIntroduction. Interpolyelectrolyte complexes (IPEC) are promising carriers for controlled drug delivery systems. The introduction of ionic API into delivery systems can lead to the formation of bonds with polyelectrolytes, which affects the release of ...
A. Yu. Sitenkov +4 more
doaj +1 more source
Clinical and Experimental Hypertension, 2017 In endothelium-denuded abdominal (but not thoracic) aortas of rats, the nonselective cyclooxygenase (COX) inhibitor, indomethacin, suppressed contractions evoked by α-adrenergic agonists hypothetically mediated by prostanoids.
Ruth M. López +8 more
doaj +1 more source
Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch +4 more
wiley +1 more source
PM&R, EarlyView.Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
In vitro and in vivo assessment of indomethacin-induced genotoxicity: protection by curcumin
Research in Pharmaceutical SciencesBackground and purpose: Indomethacin is one of the most widely used non-steroidal anti-inflammatory drugs. This study aimed to investigate the protective effects of curcumin against indomethacin-induced genotoxicity.
Ehsan Zamani +4 more
doaj +1 more source
Gastroenterology Research and Practice, 2018 Background and Aim. Rectal indomethacin was reported to be effective for postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) prophylaxis.
Xingkang He +5 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2002 We previously observed that changes in choline phospholipids of two malignant human mammary epithelial cells. (HMECs) following treatment with a high dose of the cyclooxygenase.
Kshama Natarajan +3 more
doaj +1 more source