Results 61 to 70 of about 46,561 (203)

Comparative Effects of Indomethacin and Nabumetone on Urine and Electrolyte Output in Conscious Rats

Journal of Pharmacological Sciences, 2005
The effects of indomethacin and nabumetone on urine and electrolyte excretion in conscious rats were examined. Male Sprague-Dawley rats were housed individually for a five-week duration, consisting of acclimatization, control, experimental, and recovery ...
Idris bin Long, Harbindar Jeet Singh, Gurubelli Janardhana Rao   +2 more
doaj   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

The Effect of Tramadol and Indomethacin Coadministration on Gastric Barrier Function in Dogs

Journal of Veterinary Internal Medicine, 2014
Background Tramadol is a centrally acting analgesic that is often used in conjunction with nonsteroidal anti‐inflammatory drugs (NSAIDs). The effect of coadministration of tramadol and indomethacin on gastric barrier function in dogs is unknown ...
T.L. Hill, B.D.X. Lascelles, J. M. Law, A.T. Blikslager   +3 more
doaj   +1 more source

EBNEO Commentary: Expectant Management Versus Medication for Patent Ductus Arteriosus in Preterm Infants—The PDA RCT

Acta Paediatrica, Volume 115, Issue 9, Page 2050-2051, September 2026.
Critically Appraised Summary Table (CAST) for the “Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.”
Tim Hundscheid, Willem P. de Boode
wiley   +1 more source

Indomethacin Inhibits Cancer Cell Migration via Attenuation of Cellular Calcium Mobilization

Molecules, 2013
Non-steroidal anti-inflammatory drugs (NSAIDs) were shown to reduce the risk of colorectal cancer recurrence and are widely used to modulate inflammatory responses. Indomethacin is an NSAID.
Ke-Li Tsai, Wei-Chiao Chang, Mei-Hsien Lee, Jaw-Yan Wang, Ming-Feng Hou, Yao-Ting Tsai, Yii-Her Chou, Siou-Jin Chiu, Wen-Li Hsu, Yuh-Cherng Guo, Che-Mai Chang   +10 more
doaj   +1 more source

Narrative Review on Therapies That Influence Inflammatory Responses During Extremely Premature Perinatal Respiratory Transition

Acta Paediatrica, Volume 115, Issue 9, Page 1847-1860, September 2026.
ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley   +1 more source

A Comparison Between Nifedipin and Indemethacin for the Treatment of Preterm Labor and Their Side Effects

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: This study aimed to compare the efficacy of 2 tocolytic agents of nifedipin and indomethacin for treatment of preterm labor and their complications.
B Zolali, Sh Bahasadri, M Kashanian
doaj  

Gastroprotective Effect of Selenium Nanoparticles in Indomethacin-Induced Chronic Gastritis in Adult Male Albino Rats: A Histological, Immumohistochemical and Biochemical Study [PDF]

The Egyptian Journal of Histology
Introduction: Chronic gastritis is a major health problem affecting a large percentage of population, despite being often manifested by subtle and unnoticed symptoms, it is a predisposing factor of gastric ulcers and carcinoma.Material & Methods: 24 ...
Asmaa Mohamed Shahin
doaj   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source