Results 81 to 90 of about 68,039 (253)
EBNEO Commentary: Expectant Management Versus Medication for Patent Ductus Arteriosus in Preterm Infants-The PDA RCT. [PDF]
Acta PaediatrCritically Appraised Summary Table (CAST) for the “Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial.”
Hundscheid T, de Boode WP.
europepmc +2 more sources
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
Effects of indomethacin on dams and foetuses of CS7BL/6J mice
, 1995 Normal adult inbred C57 BL/6J mice were used to investigate the teratogenic and other possible toxic effects of indomethacin on both dams and their foetuses.
Abou-Tarboush, F.M.
core
Impairment of pronephros development upon indomethacin treatment.
, 2013 (A) Overview of pronephric alterations in zebrafish larvae (50 hpf) following indomethacin administration for 24 hours. Row 1 shows control embryos, rows 2-6 zebrafish embryos following indomethacin administration in increasing concentrations (row 2, 0 ...
Philip L. Beales (492737) +7 more
core +1 more source
Cancer Science, EarlyView.Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon +6 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Indomethacin and Renal impairment in neonates
, 2015 Renal impairment occurs in neonates receiving indomethacin for treatment of patent ductus arteriosus. Inhibition of cyclooxygenase within the neonatal kidney results in decreased prostaglandin synthesis and consequent reduction in renal perfusion ...
Reynolds, Graham +4 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay +3 more
wiley +1 more source
APPLICATION OF INDOMETHACIN IN MEDICINE AND PHARMACY
, 2018 Indomethacin, a non-steroid anti-inflammatory drug (NSAID), has been used in different spheres of medicine since the 1960s. It is successfully administered as an anti-inflammatory and pain-relieving medication in rheumatoid and other diseases.
I. I. Krasnuk +7 more
core +3 more sources
Analytical Science Advances, Volume 7, Issue 2, December 2026.The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia +10 more
wiley +1 more source