Results 101 to 110 of about 68,039 (253)

The Effect of Frusemide on Indomethacin Plasma Levels

, 1974
The pharmacokinetic and clinical effects of concurrent oral indomethacin and frusemide administration were determined in eight patients with rheumatoid arthritis.
Dick, W. C., Brooks, P. M., Famaey, J. P., Sturrock, R. D.   +3 more
core  

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

MedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao, Zhaoling Li, Lianxin Zhang, Yitong Xu, Ziwei Wang, Zixun Wang, Aiden Xian, Liwen Zheng, Jingxuan Chen, Yufei Han, Chunhua Shan, Kaikai Lu, Ming Tao, Ling Zhang, Weiguang Zhang, Wei Huang, Yuhui Wang, Rui Wei, Erdan Dong, Xunde Xian   +19 more
wiley   +1 more source

Is oral indomethacin effective in treatment of preterm infants with patent ductus arteriosus?

The Turkish Journal of Pediatrics, 2004
Twenty-one preterm infants (with a mean gestational age and birth weight of 29.3 weeks and 1288.6 g) and nine pretem infants (with a mean gestational age and birth weight of 29.6 weeks and 1153.1 g) were treated with an enteral preparation of ...
Mehmet Satar, Hacer Yapicioğlu, Nejat Narli, Nazan Ozbarlas, Osman Küçükosmanoğlu, Ercan Tutak   +5 more
doaj  

Gastroprotective Effect of Selenium Nanoparticles in Indomethacin-Induced Chronic Gastritis in Adult Male Albino Rats: A Histological, Immumohistochemical and Biochemical Study [PDF]

The Egyptian Journal of Histology
Introduction: Chronic gastritis is a major health problem affecting a large percentage of population, despite being often manifested by subtle and unnoticed symptoms, it is a predisposing factor of gastric ulcers and carcinoma.Material & Methods: 24 ...
Asmaa Mohamed Shahin
doaj   +1 more source

Safety of Nonsteroidal Anti‐Inflammatory Drug Use in Traumatic Brain Injury

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 10, October 2026.
ABSTRACT Background Use of nonsteroidal anti‐inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14 days of TBI was associated with a clinically significant progression of intracranial bleed (PIB).
Jennifer Beavers, Mary Katherine Cella Shultz, Leanne Atchison, Cara Lwin, Dandan Liu, Silky Chotai, Andrew J. Medvecz, Robel Beyene, Michael C. Smith, Bradley M. Dennis, Susan Hamblin   +10 more
wiley   +1 more source

Enhanced in vitro release of indomethacin from non-aqueous suspensions using indomethacin-polyvinylpyrrolidone coprecipitate

, 1985
The release of indomethacin and indomethacin-polyvinylpyrrolidone (PVP) coprecipitate (1:1) from non-aqueous suspensions to aqueous phase has been investigated.
Oth, Marianne P., Moes, André Jules
core   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, Volume 11, Issue 18, 18 September 2026.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, Volume 13, Issue 50, 7 September 2026.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Effect of Atorvastatin on Indomethacin-Induced Gastric Ulceration in Rats: Role of Nitric Oxide and Gastric Motility

Medical Journal of Babylon
Background: Non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastric ulceration caused by inhibition of prostaglandins. Atorvastatin, a widely used hypolipidemic agent, has many beneficial pleiotropic effects like anti-inflammatory and antioxidant ...
Dilgash A. Ali, Hani M. Almukhtar
doaj   +1 more source