Children, 2023 This systematic review aimed to identify the benefits and possible harms of tocolytic therapy for preterm labour management in the context of pregnant women with extremely preterm birth, multiple gestations, or growth-restricted foetuses. A comprehensive
Noyuri Yamaji +9 more
doaj +3 more sources
In vitro study of the tocolytic effect of oroxylin A from
Journal of Biomedical Science, 2009 Scutellariae Radix is one of the well-known tocolytic Chinese herbs. Oroxylin A is isolated from the root of Scutellaria baicalensis. The main syndrome of preterm birth is caused by uterus contractions from excitatory factors. Administration of tocolytic
Yang Ling-Ling +2 more
doaj +2 more sources
School Performance After Maintenance Tocolysis With Nifedipine for Threatened Preterm Birth: 12-Year Follow-Up of the APOSTEL 2 Trial. [PDF]
BJOGABSTRACT Objective To evaluate school performance at 12 years of age in children prenatally exposed to maintenance tocolysis with nifedipine versus placebo. Design 12‐year follow‐up of the multicentre APOSTEL 2 trial, in which participants with threatened preterm birth between 26+0 and 32+2 weeks of gestation, who remained pregnant after initial 48‐h ...
van der Windt LI +8 more
europepmc +2 more sources
BMC Pregnancy and Childbirth, 2022 Background A few studies have reported that maternal administration of antenatal corticosteroids increased the risk of pulmonary edema (PE). However, despite the increasing usage rate of betamethasone as antenatal corticosteroid, maternal administration ...
Takashi Nishikawa, Ken Fukuhara
doaj +1 more source
Case Reports in Anesthesiology, 2021 Effective tocolysis is essential after fetal myelomeningocele repair and is associated with the development of pulmonary edema. The increased uterine activity in the immediate postoperative period is commonly treated with magnesium sulfate.
Denis Snegovskikh +6 more
doaj +1 more source
Nifedipine and indomethacin in preventing preterm labor under 32 gestational weeks
Gülhane Tıp Dergisi, 2022 Aims:This study compared nifedipine and indomethacin treatments, commonly used tocolytic agents, in terms of efficacy and maternal side effects.Methods:This retrospective study included pregnant women spontaneous preterm labor between 24 and 32 weeks of ...
Gülşah Dağdeviren +5 more
doaj +1 more source
Southeast Nigerian polyherbal (AJUMBISE): A potential uterotonic and tocolytic agents
Scientific African, 2020 Ajumbise is a polyherbal used by women in southeast Nigeria to enhance labor, expel retained placenta and blood clots after delivery, relief postpartum and menstrual pains and promote involution of the uterus.
S.N. Ijioma +4 more
doaj +1 more source
Comparative study of efficacy of nifedipine, nitroglycerin dermal patches and isoxsuprine as tocolytic agents in suppression of preterm labour 1-year study at navodaya medical college hospital and research centre Raichur [PDF]
, 2021 Background: Tocolytic agents are used to reduce preterm deliveries. Very few studies documenting the comparison of tocolytic agents viz. nifedipine, nitroglycerin dermal patches and isoxsuprine.
Haripriya, V., D., Rita
core +1 more source
Maternal pulmonary edema after 46 h of ritodrine hydrochloride administration: A case report
Case Reports in Women's Health, 2020 Introduction: Ritodrine hydrochloride is still widely used as a tocolytic agent in Japan, but it can cause maternal pulmonary edema, which may paradoxically induce preterm birth. Here we present a case of severe pulmonary edema due to
Tsuyoshi Murata +7 more
doaj +1 more source
Anoctamin 1 antagonism potentiates conventional tocolytic-mediated relaxation of pregnant human uterine smooth muscle [PDF]
, 2021 BACKGROUND: Currently available tocolytic agents are not effective treatment for preterm labor beyond 48 h. A major reason is the development of maternal side effects which preclude the maintenance of an effective steady-state drug concentration.
Dan, William +10 more
core +1 more source