Association between terbutaline sulfate plus ambroxol hydrochloride and clinical outcomes, pulmonary function, and inflammatory biomarkers in elderly patients with acute exacerbation of chronic obstructive pulmonary disease [PDF]
Frontiers in PharmacologyBackgroundAcute exacerbations of chronic obstructive pulmonary disease (AECOPD) are characterized by airflow limitation and marked airway/systemic inflammation, particularly in elderly patients.ObjectiveTo evaluate the association between terbutaline ...
Xin Yu +5 more
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Effectiveness of adjunctive Xiao-er Kechuanling to terbutaline and montelukast in children with uncontrolled asthma: a prospective observational cohort study [PDF]
Frontiers in PediatricsBackgroundAchieving optimal control in childhood asthma remains challenging, particularly with therapies like short-acting beta2-agonists (SABA) plus leukotriene receptor antagonists (LTRA).
Shutao Luo, Cuiyuan Li, Shaojin Huo
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Comparison of Tocolytic Agents for Successful External Cephalic Version: A Bayesian Network Meta-Analysis of Sixteen Randomized Controlled Trials [PDF]
Balkan Medical JournalBackground: Cesarean section is frequently performed for breech presentation; however, external cephalic version (ECV) is recommended as an alternative strategy to increase the likelihood of vaginal birth.
Yunyun Xiao, Jinhe Shi, Yan Dong, Lu Han
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Practice Pattern Variation in Management of Severe Acute Asthma Among Mechanically Ventilated Patients in Pediatric Versus Adult ICUs [PDF]
Critical Care ExplorationsA large multicenter retrospective study was conducted to examine practice patterns in the care of severe acute asthma in PICUs compared with adult ICUs. Eligible patients were 12–26 y old, admitted to a PICU or an adult ICU with severe acute asthma, and ...
Aaron Dobie, MD +6 more
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Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer’s disease by administration through an intranasal route [PDF]
Communications BiologyBambuterol is a long-acting anti-asthmatic prodrug which releases terbutaline. Terbutaline is an agonist of the β2-adrenergic receptors which is formed by decarbamoylation of bambuterol by butyrylcholinesterase.
Anne-Claire Groo +13 more
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Pakistan Journal of Pharmaceutical Sciences, 2022 Terbutaline have been reported to have anti-inflammatory activity. Present study aimed to check the anti-arthritic activity of terbutaline. The drug was tested using in vitro models (bovine serum albumin denaturation, egg albumin denaturation and HRBC ...
Nasser Hadal Alotaibi +9 more
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Activation of β2-adrenergic Receptor Alleviates Collagen-induced Arthritis by Ameliorating Th17/Treg Imbalance [PDF]
Iranian Journal of Immunology, 2023 Background: Recent research in our laboratory shows that CD4+ T cells express the β2 adrenergic receptor (β2-AR), and the sympathetic neurotransmitter norepinephrine regulates the function of T cells via β2-AR signaling.
Jian-Hua Lu +5 more
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Heliyon, 2023 Aims: Our aims were to investigate the uterus relaxant effect of sildenafil alone and co-administered with β2-mimetic terbutaline in an isolated organ bath and to perform in vivo smooth muscle electromyographic studies in pregnant rats. The modifications
Tamara Barna +3 more
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Acta Obstetricia et Gynecologica Scandinavica, 2023 Introduction Preterm delivery and its complications are among the biggest challenges and health risks in obstetrical practice. Several tocolytic agents are used in clinical practice, although the efficacy and side effect profiles of these drugs are not ...
Tamara Barna +5 more
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Scientific Reports, 2022 The utility of ambulatory electrocardiography (AECG) to evaluate cats with subclinical hypertrophic cardiomyopathy (HCM) for arrhythmias and heart rate variability (HRV) is not well defined but may provide information regarding risk stratification.
Ashley L. Walker +4 more
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