Results 41 to 50 of about 15,444 (165)
Background: Myelomeningocele (MMC) is a neural tube defect disease. Antenatal repair of fetal MMC is an alternative to postnatal repair. Many agents can be used as tocolytics during the in utero fetal repair such as β2-agonists and oxytocin receptor ...
Shirley Andrade Santos +11 more
doaj +1 more source
Preparation and Characterization of Terbutaline Sulphate-loaded Chitosan/Carbopol Nanoparticles [PDF]
Objective: The objective of the present study is to prepare and evaluate terbutaline sulphate loaded chitosan/carbapol nanoparticles for treatment of asthma via nasal route.
soha abd el-motelb +2 more
doaj +1 more source
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon +4 more
wiley +1 more source
Status Epilepticus Alters the Function of Brain‐Derived Extracellular Vesicles
ABSTRACT Epilepsy is a neurological disorder characterised by recurrent spontaneous seizures. Approximately 30% of patients are unable to achieve adequate seizure control with available medications, highlighting the need to better understand disease mechanisms and develop improved treatments.
Samantha L. Reed +6 more
wiley +1 more source
Terbutaline versus salbutamol for suppression of preterm labor: A randomized clinical trial
Background and Objective: Preterm labor (PTL) is a common medical problem during pregnancies and is associated with neonatal mortality and morbidity. Beta-adrenergic agonists are among the most commonly used tocolytic agents. The aim of this study was to
Motazedian Shahdokht +3 more
doaj
ABSTRACT Syntaxin‐binding protein 1 (STXBP1) mutations lead to severe epilepsy, intellectual disability, developmental delay, and movement disorder. Effective treatments for these conditions do not exist. Recent studies in Munc18‐1 (STXBP1) C. elegans models demonstrate that 4‐phenylbutyrate (4‐PBA) or related pharmacological chaperones stabilize ...
Aline Frick +2 more
wiley +1 more source
Tocolytic agents and the failure to improve neonatal outcomes
Abstract Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication. While multiple agents have been studied over the last 70 years leading to hundreds of publications and involving ...
Jack FitzSimmons, Emily Oliver
wiley +1 more source
ABSTRACT Background Skeletal muscle is essential for metabolic health and physical function. While resistance training promotes muscle hypertrophy, alternative therapeutic strategies are needed for individuals unable to engage in physical activity. Because beta2‐adrenergic stimulation induces muscle growth without mechanical load, we assessed muscle ...
Søren Jessen +9 more
wiley +1 more source
We investigated the influence of bronchodilating β2-agonists on the activity of human acetylcholinesterase (AChE) and usual, atypical and fluoride-resistant butyrylcholinesterase (BChE). We determined the inhibition potency of racemate and enantiomers of
Anita Bosak +4 more
doaj +1 more source
Background Adverse drug reactions (ADR's) could be expected more frequently in pregnant women. This study was performed in order to identify ADR's to tocolytic drugs in hospitalised pregnant women.
Palma-Aguirre José +4 more
doaj +1 more source

