Results 1 to 10 of about 22,283 (171)

Targeting β2-adrenergic receptor reduces UV-induced cutaneous damage and inflammation in a murine model [PDF]

Journal of Photochemistry and Photobiology
Preclinical studies demonstrated that the β-adrenergic receptor antagonists (β-blockers) inhibit skin damage and cancer development induced by ultraviolet (UV) radiation, but the mechanism remains unknown.
Ayaz Shahid, Rita Miwalian, Bradley T. Andresen, Steven Cole, Ying Huang   +4 more
doaj   +2 more sources

β2‐adrenergic receptor expression in patients receiving bevacizumab therapy for metastatic melanoma [PDF]

Cancer Medicine, 2023
Background Vascular endothelial growth factor (VEGF) was initially known as vascular permeability factor and identified as a driver of tumour angiogenesis.
Cornelia Schuster, Lars A. Akslen, Oddbjørn Straume   +2 more
doaj   +2 more sources

Psychological distress and tumor cell β2-adrenergic receptor levels in patients with surgically resected non-small cell lung cancer. [PDF]

Acta Oncol
Hardardottir H, Aspelund T, Valdimarsdottir B, Asmundsson J, Petursdottir V, Fall K, Broström E, Valdimarsdottir H, Fang F, Magnusson MK, Gudjonsson T, Gudbjartsson T, Sloan EK, Lutgendorf SK, Jansson C, Valdimarsdottir UA.   +15 more
europepmc   +3 more sources

Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells.

PLoS ONE, 2021
The β2-adrenergic receptor has been shown to be involved in neuroendocrine differentiation and to contribute to the development of aggressive prostate cancer.
Ilaria Guerriero, Håkon Ramberg, Krizia Sagini, Manuel Ramirez-Garrastacho, Kristin A Taskén, Alicia Llorente   +5 more
doaj   +1 more source

β2-adrenergic receptor knockout mice exhibit A diabetic retinopathy phenotype. [PDF]

PLoS ONE, 2013
There is considerable evidence from our lab and others for a functional link between β-adrenergic receptor and insulin receptor signaling pathways in retina.
Youde Jiang, Qiuhua Zhang, Li Liu, Jie Tang, Timothy S Kern, Jena J Steinle   +5 more
doaj   +1 more source

Impact of R-Carvedilol on β2-Adrenergic Receptor-Mediated Spontaneous Calcium Release in Human Atrial Myocytes

Biomedicines, 2022
A hallmark of atrial fibrillation is an excess of spontaneous calcium release events, which can be mimicked by β1- or β2-adrenergic stimulation. Because β1-adrenergic receptor blockers (β1-blockers) are primarily used in clinical practice, we here ...
Sergi Casabella-Ramón, Verónica Jiménez-Sábado, Carmen Tarifa, Sandra Casellas, Tien Tina Lu, Paloma Izquierdo-Castro, Ignasi Gich, Marcel Jiménez, Antonino Ginel, José M. Guerra, S. R. Wayne Chen, Raul Benítez, Leif Hove-Madsen   +12 more
doaj   +1 more source

Association of Gln27Glu Polymorphism of the β2-adrenoreceptor Gene with Specific Parameters of the Immunoregulatory Cytokine Cascade and IgE Production in Patients with Bronchial Asthma

Туберкулез и болезни лёгких, 2022
The objective: to study the level of serum cytokines IL-4, IFN-γ and the activity of IgE production in patients with bronchial asthma (BA) with the consideration of the Gln27Glu-polymorphism of the β2-AR gene.Subjects and Methods.
Kh. I. Turdibekov, E. N. Tashkenbaeva, Sh. Kh. Ziyadullaev, S. Kh. Ibragimov   +3 more
doaj   +1 more source

Selectivity and Maximum Response of Vibegron and Mirabegron for β3-Adrenergic Receptors

Current Therapeutic Research, 2022
: Background: The β3-adrenergic agonists vibegron and mirabegron have shown favorable safety profiles and efficacy for the treatment of overactive bladder.
Benjamin M. Brucker, MD, Jennifer King, PharmD, Paul N. Mudd, Jr, PharmD, MBA, Kimberly McHale, PhD   +3 more
doaj   +1 more source

Role of β-adrenergic receptors in insulin resistance: Induction or protection?

Zagazig Journal of Pharmaceutical Sciences, 2021
β Adrenergic receptors, in particular β2 subtype, are key regulators of glucose homeostasis. Previous studies showed that activation of hepatic and adipose tissue β adrenergic receptors mediates insulin desensitizing effects.
Wael Ibrahim , Islam Ibrahim, Amr Mahmoud , Mona Abdelaziz   +3 more
doaj   +1 more source

Augmented β2-adrenergic signaling dampens the neuroinflammatory response following ischemic stroke and increases stroke size

Journal of Neuroinflammation, 2019
Background Ischemic stroke provokes a neuroinflammatory response and simultaneously promotes release of epinephrine and norepinephrine by the sympathetic nervous system.
Kendra J. Lechtenberg, Scott T. Meyer, Janelle B. Doyle, Todd C. Peterson, Marion S. Buckwalter   +4 more
doaj   +1 more source