Results 31 to 40 of about 15,444 (165)
Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Biomedicines, 2020 Obesity is a chronic low-grade inflammatory condition, and β2-adrenergic agonists as well as exercise have been proposed as anti-inflammatory strategies in obesity, so it is critical to accurately determine the effects of β2-adrenergic stimulation ...
Leticia Martín-Cordero +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella +5 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah +7 more
wiley +1 more source
Anti-Inflammatory Effects of β2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1. [PDF]
PLoS ONE, 2016 Mitogen-activated protein kinase phosphatase 1 (MKP-1) expression is induced by inflammatory factors, and it is an endogenous suppressor of inflammatory response. MKP-1 expression is increased by PDE4 inhibitor rolipram suggesting that it is regulated by
Tiina Keränen +4 more
doaj +1 more source
Epilepsia, Volume 67, Issue 7, Page 3779-3790, July 2026.Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall +3 more
wiley +1 more source
Pediatrics and Neonatology, 2011 Inhaled β2-adrenergic receptor (β2-AR) agonists are the mainstay of treatment of acute asthma. Polymorphisms of the β2-AR, especially codons 16, 27, and 164, may affect the functions of the receptor.
Ming-Yung Lee +5 more
doaj +1 more source
Pregnancy, Volume 2, Issue 4, July 2026.Abstract Background Delayed interval delivery (DID) is a rare strategy for preterm multiple gestations where delivery of the remaining fetus(es) is intentionally delayed following the delivery of the first infant, with the goal of improving outcomes for the retained fetus(es).
Megan Stevenson +14 more
wiley +1 more source
Optimization and improvement of the synthesis method of terbutaline sulfate
Journal of Hebei University of Science and Technology, 2019 In order to obtain high yield and product quality of terbutaline sulfate, the synthetic method of terbutaline sulfate is studied. Terbutaline sulfate is synthesized from 3,5-dibenzyloxyacetophenone by bromination, alkylation reaction, carbonyl reduction ...
Xuebin ZHAO +4 more
doaj +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2023 Meng-qin Wang,1,* Ying Zhuang,1,* Ya-ning Zheng2 1Department of Obstetrics, Nanjing Drum Tower Hospital, Nanjing, People’s Republic of China; 2Department of Gynecology Otolaryngology, Nanjing Drum Tower Hospital, Nanjing, People’s Republic of ...
Wang MQ, Zhuang Y, Zheng YN
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