Results 241 to 250 of about 156,745 (364)

ATP-binding cassette transporters as possible targets for the intervention of neurodegenerative diseases. [PDF]

Neural Regen Res
Lok HC, Halliday GM, Kim WS.
europepmc   +1 more source

The Role of Specific ATP-Binding Cassette Transporters in the Acquired Resistance to Pyrrolobenzodiazepine Dimer-Containing Antibody-Drug Conjugates. [PDF]

Mol Cancer Ther, 2020
Corbett S, Huang S, Zammarchi F, Howard PW, van Berkel PH, Hartley JA.   +5 more
europepmc   +1 more source

Inhibition of ATP-Binding Cassette Transporter Downregulates Interleukin-1β-Mediated Autocrine Activation of Human Dermal Fibroblasts [PDF]

, 2001
Daniel Lottaz, Zsuzsanna Beleznay, M. Bickel   +2 more
openalex   +1 more source

Differential gene expression toward species of Aristolochia impairing the performance of the Troidini butterfly Battus polydamas

Entomologia Experimentalis et Applicata, EarlyView.
We studied the response of Battus polydamas (Papilionidae) larvae fed on Aristolochia ringens (containing several diterpenes) and Aristolochia gigantea (containing sesquiterpenes and acyclic monoterpenoids but no diterpenoids or aristolochic acids). We assessed larval performance on fitness components such as survival and differential gene expression ...
Karina L. Silva‐Brandão, Clécio Fernando Klitzke, Marcelo M. Brandão, José Roberto Trigo   +3 more
wiley   +1 more source

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

, 2001
Charles Joyce, Marcelo Amar, Gilles Lambert, Boris Vaisman, Beverly Paigen, Jamila Najib-Fruchart, Robert F. Hoyt, Edward D. Neufeld, Alan T. Remaley, Donald S. Fredrickson, H Bryan Brewer, Silvia Santamarina-Fojo   +11 more
openalex   +1 more source

Metabolomic and proteomic stratification of equine osteoarthritis

Equine Veterinary Journal, EarlyView.
Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson, Marie M. Phelan, Eva Caamaño‐Gutiérrez, Peter D. Clegg, Luis M. Rubio‐Martinez, Mandy J. Peffers   +5 more
wiley   +1 more source

Regulation of ATP-binding Cassette Sterol Transporters ABCG5 and ABCG8 by the Liver X Receptors α and β [PDF]

, 2002
Joyce J. Repa, Knut Erik Berge, Chris Pomajzl, James A. Richardson, Helen H. Hobbs, David J. Mangelsdorf   +5 more
openalex   +1 more source

Synovial fluid alpha‐2‐macroglobulin, gelsolin and lubricin distinguish between osteoarthritic and healthy equine joints

Equine Veterinary Journal, EarlyView.
Abstract Background Synovial fluid (SF) is an ideal sentinel fluid for osteoarthritis (OA) diagnosis and prognostication due to its critical homeostatic role, proximity to articular tissues and immune cell composition. Untargeted proteomics enable identification of soluble markers for diagnostic and therapeutic applications while minimising bias ...
Erica J. Secor, Sydney J. Womack, Machiel P. Ysebaert, Marshall J. Colville, Heidi L. Reesink   +4 more
wiley   +1 more source

The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter [PDF]

, 2002
Elizabeth L. Borths, Kaspar P. Locher, Allen T. Lee, Douglas C. Rees   +3 more
openalex   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

The FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source