Results 171 to 180 of about 60,219 (305)

Action of 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibitors on ABCA-1 protein (ATP-Binding Cassette Transporter-1) in endothelial cells stimulated with uremic serum. [PDF]

Lipids Health Dis
de Melo Carmona S, Jardim DP, Dalboni MA, Nakamichi R, Kuniyoshi M, Marrocos M, Quinto BMR, Batista MC.   +7 more
europepmc   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Investigating the Effect of Aspirin on apoAI-Induced ATP Binding Cassette Transporter 1 Protein Expression and Cholesterol Efflux in Human Astrocytes. [PDF]

Adv Biomed Res
Nazeri Z, Abdeveiszadeh N, Zarezade V, Azizidoost S, Cheraghzadeh M, Aberumand M, Kheirollah A.   +6 more
europepmc   +1 more source

Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2

Rheumatology &Autoimmunity, EarlyView.
Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li, Guo Tang, Ye Yu, Guang‐Liang Chen, Liangjing Lu, Juan Wang   +5 more
wiley   +1 more source

Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1

, 2010
Cholesterol plays an important role in the HIV life cycle, and infectivity of cholesterol-depleted HIV virions is significantly impaired. Recently, we demonstrated that HIV-1, via its pro-tein Nef, inhibits the activity of the major cellular cholesterol ...
Lucas Jennelle, Alan T. Remaley, Nigora Mukhamedova, Zahedi Mujawar, Tatiana Pushkarsky, Fatah Kashanchi, Larisa Dubrovsky, Michael Bukrinsky, Angela Grant, Yana Kiselyeva, Dmitri Sviridov, Matthew P. Morrow   +11 more
core  

Approaching Gold‐Standard Sensitivity in a Portable and Versatile Gold Nanoprisms Thermoplasmonic Platform for Lateral Flow Detection of Biomolecules

Small, EarlyView.
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón, Alba Martín Barreiro, África García Barrientos, María Moros, Valeria Grazú Bonavía, Jesús Martínez de la Fuente   +5 more
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Bempedoic acid within the phase ternary diagram governing biliary cholesterol solubilization and gallstone risk. [PDF]

J Lipid Res
Di Ciaula A, Khalil M, Garruti G, Portincasa P.   +3 more
europepmc   +1 more source

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

The Molecular Mechanisms of Metformin's Action on Blood Lipid Profile in Diabetic Patients. [PDF]

Int J Mol Sci
Dettlaff-Pokora A, Swierczynski J.
europepmc   +1 more source