Results 51 to 60 of about 30,215 (258)
Cells, 2021 Macrophage stimulation by pathogen-associated molecular patterns (PAMPs) like lipopolysaccharide (LPS) or lipoteichoic acid (LTA) drives a proinflammatory phenotype and induces a metabolic reprogramming to sustain the cell’s function.
Anna Santarsiero +9 more
doaj +1 more source
Nuclear mutations affecting mitochondrial structure and function in Chlamydomonas [PDF]
, 1977 Wild type cells of the green alga Chlamydomonas reinhardtii can grow in the in the dark by taking up and respiring exogenously supplied acetate. Obligate photoautotrophic (dark dier, dk) mutants of this alga have been selected which grow at near wild ...
Boynton, J. E. +2 more
core +1 more source
Frontiers in Immunology, 2018 Metabolism in immune cells is no longer thought of as merely a process for adenosine triphosphate (ATP) production, biosynthesis, and catabolism. The reprogramming of metabolic pathways upon activation is also for the production of metabolites that can ...
Niamh C. Williams, Luke A. J. O’Neill
doaj +1 more source
Citrinin Derivatives From Penicillium Citrinum Y34 That Inhibit α-Glucosidase and ATP-Citrate Lyase
Frontiers in Marine Science, 2022 Two new citrinin dimers bearing a 6,6-spiroketal moiety (1 and 2) and four known analogues (3–6), together with 18 known citrinin monomers (7–24), were isolated from the culture of hydrothermal vent-associated fungus Penicillium citrinum Y34.
Shanji Chen +18 more
doaj +1 more source
Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway. [PDF]
, 2018 The Calvin-Benson-Bassham (CBB) cycle is presumably evolved for optimal synthesis of C3 sugars, but not for the production of C2 metabolite acetyl-CoA.
Chuang, Derrick S +4 more
core +1 more source
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
Cell Reports, 2016 Mechanisms of metabolic flexibility enable cells to survive under stressful conditions and can thwart therapeutic responses. Acetyl-coenzyme A (CoA) plays central roles in energy production, lipid metabolism, and epigenomic modifications.
Steven Zhao +18 more
doaj +1 more source
Changes in the microsomal proteome of tomato fruit during ripening [PDF]
, 2019 The variations in the membrane proteome of tomato fruit pericarp during ripening have been investigated by mass spectrometry-based label-free proteomics.
De Lorenzo, Giulia +6 more
core +1 more source
Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]
, 2016 AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano +3 more
core +2 more sources
Renal citrate metabolism and urinary citrate excretion in the infant rat [PDF]
, 2000 Renal citrate metabolism and urinary citrate excretion in the infant rat.BackgroundAlthough hypercalciuria has the same prevalence in children as adults, children rarely develop renal stones.
Melnick, Joel Z. +3 more
core +4 more sources
Advanced Science, EarlyView.Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang +14 more
wiley +1 more source