Results 111 to 120 of about 795,957 (364)

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

open access: yesAdvanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez   +2 more
wiley   +1 more source

ATP Hydrolysis by RAD50 Protein Switches MRE11 Enzyme from Endonuclease to Exonuclease*

open access: yesJournal of Biological Chemistry, 2011
Background: RAD50-MRE11-Nbs1 complex is essential for DNA repair. Results: ATP binding by RAD50 closes the complex; MRE11 is an endonuclease. ATP hydrolysis opens the complex; MRE11 is an exonuclease.
J. Majka   +4 more
semanticscholar   +1 more source

Surface Modification of Sol–Gel Synthesized Ba0.85Ca0.15Zr0.1Ti0.9O3 using Stearic Acid Additives

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores a novel approach to enhance the piezoelectric performance of lead‐free BCZT ceramics synthesized via the sol–gel method. By coating the BCZT powder with only a 0.69 nm stearic acid layer, the electromechanical response is significantly boosted up to 359 pC N−1, revealing promising implications for high‐performance sensor and ...
Michelle Weichelt   +6 more
wiley   +1 more source

Kinetics of MSC-based enzyme therapy for immunoregulation

open access: yesJournal of Translational Medicine, 2019
Background Mesenchymal stromal cells (MSC) demonstrate innate and regulatory immunologic functions and have been widely explored for cell therapy applications.
Alexandra Burr, Biju Parekkadan
doaj   +1 more source

Identification of Residues in Chromodomain Helicase DNA-Binding Protein 1 (Chd1) Required for Coupling ATP Hydrolysis to Nucleosome Sliding*

open access: yesJournal of Biological Chemistry, 2011
Background: Chromatin remodelers slide nucleosomes in an ATP-dependent manner. Results: Residues between the ATPase motor and DNA-binding domain of chromodomain helicase DNA-binding protein 1 (Chd1) are required for sliding but not nucleosome-stimulated ...
Ashok Patel   +3 more
semanticscholar   +1 more source

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

open access: yes, 2014
The replicative mini-chromosome-maintenance 2-7 (MCM2-7) helicase is loaded in Saccharomyces cerevisiae and other eukaryotes as a head-to-head double-hexamer around origin DNA.
Alberto Riera   +39 more
core   +1 more source

Unlocking the Power of Quercetin‐Encapsulated Mesoporous Bioactive Glass Nanoparticles: A Multifunctional Approach to Bone Regeneration

open access: yesAdvanced Engineering Materials, EarlyView.
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello   +5 more
wiley   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

open access: yesAdvanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou   +2 more
wiley   +1 more source

Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants

open access: yeseLife, 2018
The innate immune sensor retinoic acid-inducible gene I (RIG-I) detects cytosolic viral RNA and requires a conformational change caused by both ATP and RNA binding to induce an active signaling state and to trigger an immune response.
Charlotte Lässig   +5 more
doaj   +1 more source

Collective force generated by multiple biofilaments can exceed the sum of forces due to individual ones

open access: yes, 2014
Collective dynamics and force generation by cytoskeletal filaments are crucial in many cellular processes. Investigating growth dynamics of a bundle of N independent cytoskeletal filaments pushing against a wall, we show that chemical switching (ATP/GTP ...
Das, Dibyendu   +2 more
core   +2 more sources

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