Results 31 to 40 of about 697,459 (324)
Physical Review Research, 2022 Cellular ATP plays an important role in the calcium oscillation signal transduction pathway of pancreatic β cells. It triggers oscillation by binding the ATP-sensitive K^{+} channels (K_{ATP}), and maintains the oscillation by providing ATP hydrolysis ...
Yunsheng Sun +6 more
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Characterization of ATP hydrolysis in the Hsp70 BiP nucleotide binding domain [PDF]
Hiller S, Mas G.
europepmc +2 more sources
Pathway of processive ATP hydrolysis by kinesin [PDF]
Nature, 1995 Direct measurement of the kinetics of kinesin dissociation from microtubules, the release of phosphate and ADP from kinesin, and rebinding of kinesin to the microtubule have defined the mechanism for the kinesin ATPase cycle. The processivity of ATP hydrolysis is ten molecules per site at low salt concentration but is reduced to one ATP per site at ...
S P, Gilbert +3 more
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Zooming in on ATP Hydrolysis in F1 [PDF]
Journal of Bioenergetics and Biomembranes, 2005 We summarize our current view of the reaction mechanism in F(1)-ATPase as it has emerged from experiment, theory, and computational studies over the last several years. ATP catalysis in the catalytic binding pockets of F(1) takes place without the release of any significant free energy and is efficiently driven by the combined action of two water ...
Markus, Dittrich, Klaus, Schulten
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mBio, 2020 In Escherichia coli, FtsEX coordinates peptidoglycan (PG) synthesis and hydrolysis at the septum. It acts on FtsA in the cytoplasm to promote recruitment of septal PG synthetases and recruits EnvC, an activator of septal PG hydrolases, in the periplasm ...
Shishen Du +2 more
doaj +1 more source
eLife, 2021 Hydrolysis of nucleoside triphosphates releases similar amounts of energy. However, ATP hydrolysis is typically used for energy-intensive reactions, whereas GTP hydrolysis typically functions as a switch.
Taylor B Updegrove +11 more
doaj +1 more source
Molecular Mechanism of ATP Hydrolysis in an ABC Transporter
ACS Central Science, 2018 Hydrolysis of nucleoside triphosphate (NTP) plays a key role for the function of many biomolecular systems. However, the chemistry of the catalytic reaction in terms of an atomic-level understanding of the structural, dynamic, and free energy changes ...
Marten Prieß +3 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 The F1-ATPase is a rotary motor fueled by ATP hydrolysis. Its rotational dynamics have been well characterized using single-molecule rotation assays. While F1-ATPases from various species have been studied using rotation assays, the standard model for ...
Hiroyuki Noji, Hiroshi Ueno
doaj +1 more source
Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases
Nature Communications, 2022 The rotary ATPases use a rotary catalytic mechanism to drive transmembrane proton movement powered by ATP hydrolysis. Here, the authors report a collection of V/A-ATPase V1 domain structures, providing insights into rotary mechanism of the enzyme and ...
J. Kishikawa +7 more
doaj +1 more source
Science, 2018 Molecular-motor coordination The proteasome is a cytosolic molecular machine that recognizes and degrades unneeded or damaged proteins that have been tagged with ubiquitin.
A. H. de la Peña +4 more
semanticscholar +1 more source