Results 51 to 60 of about 795,957 (364)

ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex [PDF]

, 2019
ATP-dependent DNA end recognition and nucleolytic processing are central functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair. However, it is still unclear how ATP binding and hydrolysis primes the MR function and regulates repair ...
Cho, Y, Gwon, G, Jo, A, Kim, AK, Kim, T, Kim, Y, Lee, SE, Li, FY, Liu, Y, Song, OK, Sung, S   +10 more
core   +1 more source

The lid domain of Caenorhabditis elegans Hsc70 influences ATP turnover, cofactor binding and protein folding activity. [PDF]

PLoS ONE, 2012
Hsc70 is a conserved ATP-dependent molecular chaperone, which utilizes the energy of ATP hydrolysis to alter the folding state of its client proteins. In contrast to the Hsc70 systems of bacteria, yeast and humans, the Hsc70 system of C. elegans (CeHsc70)
Li Sun, Franziska T Edelmann, Christoph J O Kaiser, Katharina Papsdorf, Andreas M Gaiser, Klaus Richter   +5 more
doaj   +1 more source

Negative Cooperativity in the Nitrogenase Fe Protein Electron Delivery Cycle [PDF]

, 2016
Nitrogenase catalyzes the ATP-dependent reduction of dinitrogen (N2) to two ammonia (NH3) molecules through the participation of its two protein components, the MoFe and Fe proteins.
Antony, Edwin, Danyal, Karamatullah, Dean, Dennis R., Duval, Simon, Hoffman, Brian M., Horitani, Masaki, Lukoyanov, Dmitriy, Marts, Amy R., Page, Taylor R., Raugei, Simone, Seefeldt, Lance C., Shaw, Sudipta   +11 more
core   +2 more sources

Regulation of Ecto-5´-Nucleotidase by Docosahexaenoic Acid in Human Endothelial Cells

Cellular Physiology and Biochemistry, 2013
Background/Aims: Modulation of extracellular adenine nucleotide and adenosine concentrations is one potential mechanism by which docosahexaenoic acid (DHA) may exert beneficial effects in critically ill patients.
Vu Thi Thom, Martina Wendel, Andreas Deussen   +2 more
doaj   +1 more source

Phosphorus Chemistry at the Roots of Bioenergetics: Ligand Permutation as the Molecular Basis of the Mechanism of ATP Synthesis/Hydrolysis by F_OF₁-ATP Synthase

Molecules, 2023
The integration of phosphorus chemistry with the mechanism of ATP synthesis/hydrolysis requires dynamical information during ATP turnover and catalysis. Oxygen exchange reactions occurring at β-catalytic sites of the FOF1-ATP synthase/F1-ATPase imprint a
Sunil Nath
doaj   +1 more source

Unidirectional Transport Mechanism in an ATP Dependent Exporter [PDF]

, 2017
ATP-binding cassette (ABC) transporters use the energy of ATP binding and hydrolysis to move a large variety of compounds across biological membranes.
Bernèche, Simon, Seelig, Anna, Xu, Yanyan   +2 more
core   +4 more sources

Energy interconversion by the sarcoplasmic reticulum Ca2+-ATPase: ATP hydrolysis, Ca2+ transport, ATP synthesis and heat production

Anais da Academia Brasileira de Ciências, 2000
The sarcoplasmic reticulum of skeletal muscle retains a membrane bound Ca2+-ATPase which is able to interconvert different forms of energy. A part of the chemical energy released during ATP hydrolysis is converted into heat and in the bibliography it is ...
LEOPOLDO DE MEIS
doaj   +1 more source

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein

eLife, 2023
CFTR, the anion channel mutated in cystic fibrosis patients, is a model ABC protein whose ATP-driven conformational cycle is observable at single-molecule level in patch-clamp recordings.
Márton A Simon, Iordan Iordanov, Andras Szollosi, László Csanády   +3 more
doaj   +1 more source

The bacterial flagellar protein export apparatus processively transports flagellar proteins even with extremely infrequent ATP hydrolysis

Scientific Reports, 2014
For self-assembly of the bacterial flagellum, a specific protein export apparatus utilizes ATP and proton motive force (PMF) as the energy source to transport component proteins to the distal growing end.
T. Minamino, Yusuke V. Morimoto, M. Kinoshita, P. Aldridge, K. Namba   +4 more
semanticscholar   +1 more source

Analyzing conformational changes in single FRET-labeled A1 parts of archaeal A1AO-ATP synthase

, 2018
ATP synthases utilize a proton motive force to synthesize ATP. In reverse, these membrane-embedded enzymes can also hydrolyze ATP to pump protons over the membrane.
Börsch, Michael, Grueber, Gerhard, Sielaff, Hendrik, Singh, Dhirendra   +3 more
core   +1 more source