Results 121 to 130 of about 275,929 (264)

Ion-Dependent ATPase Activity and Metabolic Gene Expression in TNF-α-Challenged Skeletal Muscle Cells: Mechanistic Characterisation of Carvacrol's Bioenergetic Effects. [PDF]

Int J Mol Sci
Albarrati AM, Nazer RI.
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Evolutionary Prevalence of the Electrostatic Switch Mechanism in P-type ATPases. [PDF]

J Membr Biol
S Badve N, V Buda A, A Káral J, Li Z, L Percival T, Y Wardman S, Tran SG, Ho SYW, Clarke RJ.   +8 more
europepmc   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

The Antidepressant Drug Clomipramine Inhibits the ABC Transporter BmrA. [PDF]

Chembiochem
Hellmann N, Kersten C, Efferth T, Schneider D.   +3 more
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Impact of salt concentration and free magnesium on human beta-cardiac myosin reveal important details about the conserved mechanochemical mechanism. [PDF]

J Biol Chem
Ge J, Ebert MR, Bodt SML, Majumder S, Ma W, Yengo CM.   +5 more
europepmc   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

ProAD – A database of rotary ion-translocating ATPases in prokaryotic genomes

Frontiers in Molecular Biosciences
A. V. Litvin, A. V. Litvin, A. V. Litvin, A. S. Lapashina, A. P. Ermidis, M.S. Gelfand, B. A. Feniouk, B. A. Feniouk   +7 more
doaj   +1 more source

MCM8-9 helicase activity protects primordial germ cell development to prevent premature ovarian insufficiency. [PDF]

Proc Natl Acad Sci U S A
Jiao X, Li Z, Tang Z, Xu J, Lu LY, Liu Y.   +5 more
europepmc   +1 more source