Results 151 to 160 of about 275,929 (264)
Allelic Analysis of <i>smc-6</i> Reveals Domain-Specific Roles in DNA Repair in <i>Caenorhabditis elegans</i>. [PDF]
Liang Y +5 more
europepmc +1 more source
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu +7 more
wiley +1 more source
Correction: An atypical F-type ATPase is necessary for the function of the antibody cleavage system MIB-MIP in mycoplasmas. [PDF]
PLOS Pathogens Editors.
europepmc +1 more source
Strategies and mechanisms of precision genome engineering: From gene editing to genome writing
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang +19 more
wiley +1 more source
Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concern. [PDF]
Brice AM, Caputo AT, Stewart CR.
europepmc +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
A Highly Conserved Glycine in a Hotspot for Neurological Disease Mutations in Na<sup>+</sup>,K<sup>+</sup>-ATPase Is Critical to Na<sup>+</sup> and K<sup>+</sup> Occlusion. [PDF]
Toustrup-Jensen MS +3 more
europepmc +1 more source
Climate change demands accelerated plant adaptation and de novo domestication. Yet current enviromics focuses disproportionately on external environments, neglecting internal dynamics—gene expression, metabolic flux, and signal transduction—within predictive envirotyping frameworks.
Lin‐An Zhang +8 more
wiley +1 more source

