Results 221 to 230 of about 619,710 (391)

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

open access: yesAngewandte Chemie International Edition, Accepted Article.
Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation in 1964, it has attracted the interest of synthetic organic chemists due to its exceptional polarity, complex architecture, and important biological activity.
Benedikt Nißl   +6 more
wiley   +1 more source

Imaging‐Based High‐Content Screening with Clickable Probes Identifies XPB Inhibitors

open access: yesAngewandte Chemie International Edition, Accepted Article.
High‐content screening (HCS) has become a powerful tool in drug discovery; however, its reliance on indirect readouts and surrogate markers limits HCS’s ability to directly assess drug‐protein interactions at endogenous levels, particularly in subcellular contexts.
Shuqi Li   +10 more
wiley   +1 more source

Lipid Requirement of Membrane‐Bound ATPase [PDF]

open access: bronze, 1973
B. Roelofsen, L.L.M. Van Deenen
openalex   +1 more source

Designing New Natural‐Mimetic Phosphatidic Acid: a Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research

open access: yesAngewandte Chemie International Edition, Accepted Article.
Glycerophospholipids (GPLs) play important roles in cellular compartmentalization and signaling. Among them, phosphatidic acids (PA) exist as many distinct species depending on acyl chain composition, each one potentially displaying unique signaling function.
Antoine Schlichter   +29 more
wiley   +1 more source

INTRARENAL DISTRIBUTION AND ATPase INHIBITING ACTIVITY OF OUABAIN IN DOGS

open access: gold, 1976
Hideya Saito   +3 more
openalex   +1 more source

Dietary supplement of sodium butyrate improves the growth performance and intestinal health by targeting Wnt/β‐catenin signaling pathway in rabbits

open access: yesAnimal Research and One Health, EarlyView.
Dietary supplement of sodium butyrate, may relate to regulating intestinal health and thus the growth performance and meat quality of rabbits by regulating the continuous process of promoting the periodic cycle of cecal epithelial cells. Abstract Supplementation of sodium butyrate (SB) has been proved to be beneficial for improving the growth ...
Mengke Ni   +8 more
wiley   +1 more source

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