Results 91 to 100 of about 694,618 (329)
Characterization of Breakthrough Hemolysis in Patients With Paroxysmal Nocturnal Hemoglobinuria: An International Multicenter Experience
American Journal of Hematology, EarlyView.ABSTRACT
Breakthrough hemolysis (BTH) is defined as a hemolytic exacerbation in a patient with paroxysmal nocturnal hemoglobinuria (PNH) treated with complement inhibitors (CIs). In the current era of several terminal and proximal inhibitors, there are no guidelines for defining BTH and its severity, and clinical management is not standardized.Bruno Fattizzo, Giacinto Luca Pedone, Elisabetta Metafuni, Eloise Beggiato, Valentina Giai, Esther Natalie Oliva, Antony Ricchiuti, Marta Bortolotti, Simona Raso, Daniela Carlino, Mara Memoli, Sofia Vecchi, Jennifer Vidler, Sukanya Gogoi, Shreya Goel, Anna Corby, Roochi Trikha, Sneha Balakrishnan, Francesco Passamonti, Anna Paola Iori, Simona Sica, Shreyans Gandhi, Wilma Barcellini, Austin Kulasekararaj +23 morewiley +1 more source2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)
Revista Española de Cardiología, 2021 G. Hindricks, T. Potpara, N. Dagres, E. Arbelo, Jeroen J. Bax, C. Blomström-Lundqvist, G. Boriani, M. Castellà, G. Dan, P. Dilaveris, L. Fauchier, G. Filippatos, J. Kalman, M. la Meir, D. Lane, J. Lebeau, M. Lettino, G. Lip, F. Pinto, G. Thomas, M. Valgimigli, I. V. Van Gelder, B. V. Van putte, C. Watkins +23 moresemanticscholar +1 more sourceManagement of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT
Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash +9 morewiley +1 more sourceLarge-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation.
New England Journal of Medicine, 2019 BACKGROUND
Optical sensors on wearable devices can detect irregular pulses. The ability of a smartwatch application (app) to identify atrial fibrillation during typical use is unknown.M. Perez, K. Mahaffey, H. Hedlin, J. Rumsfeld, Ariadna Garcia, Todd Ferris, V. Balasubramanian, A. Russo, Amol Rajmane, L. Cheung, Grace Hung, Justin Lee, P. Kowey, N. Talati, Divya Nag, Santosh E. Gummidipundi, A. Beatty, M. Hills, S. Desai, C. Granger, M. Desai, M. Turakhia +21 moresemanticscholar +1 more sourceEffect of Renal Denervation and Catheter Ablation vs Catheter Ablation Alone on Atrial Fibrillation Recurrence Among Patients With Paroxysmal Atrial Fibrillation and Hypertension: The ERADICATE-AF Randomized Clinical Trial.
Journal of the American Medical Association (JAMA), 2020 Importance
Renal denervation can reduce cardiac sympathetic activity that may result in an antiarrhythmic effect on atrial fibrillation.
Objective
To determine whether renal denervation when added to pulmonary vein isolation enhances long-term ...J. Steinberg, V. Shabanov, Dmitry Ponomarev, D. Losik, Eduard Ivanickiy, E. Kropotkin, Konstantin Polyakov, P. Ptaszyński, B. Keweloh, Christopher J Yao, E. Pokushalov, A. Romanov +11 moresemanticscholar +1 more sourceDisease Characteristics and Treatments Associated with Outcome in Primary Angiitis of the Central Nervous System—A Multicenter Cohort Study in 163 Patients
Annals of Neurology, EarlyView.Objective
The aim was to determine patient, disease, and treatment characteristics associated with outcome in patients with primary angiitis of the central nervous system (PACNS) in a large multicenter German cohort. Methods
In a retrospective, observational cohort study, we analyzed 163 adult patients who met the diagnostic criteria for PACNS.Anna Lena Fisse, Nadine Bonberg, Carolin Beuker, Claudia Pfeuffer, Andreas Heidenreich, Christina Krüger, Milani Deb‐Chatterji, Jana Becker, Stefan T. Gerner, Clemens Küpper, Louisa Nitsch, Roxane‐Isabelle Kestner, Lars Udo Krause, Juliane Herm, Alexander Katalinic, André Karch, Ralf Gold, Heinz Wiendl, Wolf‐Rüdiger Schäbitz, Gabor C. Petzold, Waltraud Pfeilschifter, Marius Ringelstein, Thorsten R. Doeppner, Lars Kellert, Hagen B. Huttner, Markus Kraemer, Tim Magnus, Karl Georg Haeusler, Heike Minnerup, Jens Minnerup +29 morewiley +1 more sourceNoradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy
The Anatomical Record, EarlyView.Abstract
Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar +15 morewiley +1 more sourceExpert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis
Arthritis &Rheumatology, EarlyView.Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...Giovanni Adami, Kenneth G. Saagwiley +1 more sourceAntithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation
New England Journal of Medicine, 2019 BACKGROUND Appropriate antithrombotic regimens for patients with atrial fibrillation who have an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI) are unclear. METHODS In an international trial with a two‐by‐two factorial R. Lopes, G. Heizer, R. Aronson, A. Vora, Tyler Massaro, R. Mehran, S. Goodman, S. Windecker, H. Darius, Jia Li, O. Averkov, Cecilia M. Bahit, O. Berwanger, A. Budaj, Z. Hijazi, A. Parkhomenko, P. Sinnaeve, R. Storey, H. Thiele, D. Vinereanu, C. Granger, J. Alexander +21 moresemanticscholar +1 more source