Results 91 to 100 of about 460,135 (253)

The search for atrial fibrillation and its impact on public health

Swiss Medical Weekly, 2017
Atrial fibrillation may be clearly symptomatic and is easily amenable to state-of-the-art treatment, most importantly oral anticoagulation therapy for the prevention of thromboembolism.
Anna Lam, Eleni Goulouti, Laurent Roten
doaj   +1 more source

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire, Andrew T. Lambarth, Ayesha Saleem, Daniel R. Burrage   +3 more
wiley   +1 more source

Warfarin time in therapeutic range of primary healthcare patients in the Western Cape Province, South Africa

British Journal of Clinical Pharmacology, EarlyView.
Introduction Warfarin therapy is the mainstay of anticoagulation treatment in South Africa and requires frequent INR monitoring due to interindividual patient variability. Time in therapeutic range (TTR) reflects the proportion of total treatment time during which INR values are within therapeutic range.
Masudah Paleker, Christopher Kelly, Robin Dyers, Eric Decloedt   +3 more
wiley   +1 more source

Comparing outcomes using low‐dose apixaban and anti‐Xa monitoring and vitamin K antagonists in patients with renal replacement therapy

British Journal of Clinical Pharmacology, EarlyView.
Background Guidelines recommend oral anticoagulation for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism. Outside the United States, apixaban is unlicensed for use in patients with end‐stage renal disease (ESRD) receiving renal replacement therapy (RRT).
John K. Bartoli‐Abdou, Alexander T. Cohen, Lucy Vernon, Victoria Collings, Ubonphan Chaichana, Natasha Moore, Hamda Jibril, Li Wei, Nicola Kumar, Karen A. Breen, Andrew J. Doyle   +10 more
wiley   +1 more source

Radiofrequency ablation using the ThermoCool SmartTouch Catheter guided by ablation index versus antiarrhythmic drugs in atrial fibrillation treatment in China: a cost-consequence analysis

Journal of Comparative Effectiveness Research
Aim: To evaluate the costs and consequences of two front-line atrial fibrillation (AF) treatments from Chinese healthcare system perspective: radiofrequency catheter ablation (RFCA) using ThermoCool SmartTouch Catheter guided by Ablation Index (STAI ...
Biqi Zhang, Jie Han, Dongchen Zhou, Jiajia Jiang, Jiawei Zhong, Yunlong Lu, Chenyu Zuo, Xingwei Lu, Jianwei Xuan, Aohan Zu, Yuxian He, Xingang Sun, Lu Chen, Liangrong Zheng   +13 more
doaj   +1 more source

N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes [PDF]

, 2011
Background and Objective: The slow delayed rectifier current (IKs) is important for cardiac action potential termination. The underlying channel is composed of Kv7.1 α-subunits and KCNE1 β-subunits.
Takac, Ina, Ehrlich, Joachim, Zenawit Girmatsion, Biliczki, Peter, Biliczki Peter, Stefan H Hohnloser, Stefan H. Hohnloser, Schwerthelm Christin, Hohnloser, Stefan H., Christin Schwerthelm, Girmatsion, Zenawit, Joachim R. Ehrlich, Hohnloser Stefan H., Ina Takac, Takac Ina, Peter Biliczki, Ehrlich Joachim R., Girmatsion Zenawit, Schwerthelm, Christin, Joachim R Ehrlich   +19 more
core   +2 more sources

Patient preferences for medicines information in cardiovascular disease and the influence of unmet needs on medication adherence: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
A survey of 313 Australians with cardiovascular disease found strong preferences for digitally delivered medicine information. Half of participants reported unmet information needs related to their medicines, which were associated with lower medication adherence.
Lachlan L. Dalli, Susie Cartledge, Caroline Trin, Zuhayr Alji, Justine Causing, Monique F. Kilkenny, Antonia Arfaras, Stella Talic   +7 more
wiley   +1 more source

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

, 2019
To the Editor: Pluymaekers et al. (April 18 issue)(1) evaluated the occurrence of spontaneous cardioversion in patients with recent-onset (<36 hours) atrial fibrillation. The proposed wait-and-see approach included cardioversion within 48 hours in the
Crijns, Harry J. G. M., Dudink, Elton A. M. P., Pluymaekers, Nikki A. H. A.   +2 more
core   +1 more source

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Atrial Fibrillation: A Review of Recent Studies with a Focus on Those from the Duke Clinical Research Institute

Scientifica, 2014
Atrial fibrillation is the most common arrhythmia and accounts for one-third of hospitalizations for rhythm disorders in the United States. The prevalence of atrial fibrillation averages 1% and increases with age.
Meena P. Rao, Sean D. Pokorney, Christopher B. Granger   +2 more
doaj   +1 more source