Results 21 to 30 of about 694,618 (329)

Ibandronate promotes autophagy by inhibiting Rac1–mTOR signaling pathway in vitro and in vivo

Cell Death Discovery, 2022
We previously reported that ibandronate (IBAN) could improve endothelial function in spontaneously hypertensive rats. However, the mechanism by which IBAN improves endothelial function is unclear.
Jie Han, Jian Yang, Qiqi Wang, Xiang Yin, Zewei Sun, Chaoyang Huang, Guoping Chen, Liangrong Zheng, Dongmei Jiang   +8 more
doaj   +1 more source

Incidence, duration, pattern, and burden of de novo atrial arrhythmias detected by continuous ECG monitoring using an implantable loop recorder following ablation of the cavotricuspid isthmus

Cardiovascular Digital Health Journal, 2020
Background: Following cavotricuspid isthmus (CTI) ablation, many patients with atrial flutter (AFL) are diagnosed with atrial fibrillation (AF). The incidence, duration, pattern, and burden of AF remain undefined.
Dan L. Musat, MD, Nicolle S. Milstein, MS, Jacqueline Pimienta, MBS, Advay Bhatt, MD, FHRS, Mark W. Preminger, MD, Tina C. Sichrovsky, MD, Laura Flynn, APN, Carissa Pistilli, APN, Richard E. Shaw, PhD, Suneet Mittal, MD, FHRS   +9 more
doaj   +1 more source

Recruited macrophages elicit atrial fibrillation

Science, 2023
Atrial fibrillation disrupts contraction of the atria, leading to stroke and heart failure. We deciphered how immune and stromal cells contribute to atrial fibrillation.
M. Hulsmans, Maximilian J. Schloss, I-Hsiu Lee, Aneesh Bapat, Y. Iwamoto, Claudio Vinegoni, Alexandre Paccalet, Masahiro Yamazoe, J. Grune, S. Pabel, Noor Momin, H. Seung, Nina Kumowski, Fadi E. Pulous, Daniel Keller, C. Bening, Ursula Green, J. Lennerz, R. Mitchell, A. Lewis, B. Casadei, O. Iborra-Egea, A. Bayés‐Genís, Samuel Sossalla, C. Ong, R. Pierson, J. Aster, David Rohde, G. Wojtkiewicz, R. Weissleder, F. Swirski, G. Tellides, G. Tolis, S. Melnitchouk, D. Milan, P. Ellinor, K. Naxerova, M. Nahrendorf   +37 more
semanticscholar   +1 more source

Catheter ablation of atrial fibrillation in patients with diabetes mellitus

Heart Rhythm O2, 2020
Background: Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). Few studies have compared clinical outcomes after catheter ablation between patients with and those without DM.
Allen Wang, MD, Tracy Truong, MB, Eric Black-Maier, MD, Cynthia Green, PhD, Kristen B. Campbell, PharmD, Adam S. Barnett, MD, Janice Febre, BSN, RN, Zak Loring, MD, MHS, Sana M. Al-Khatib, MD, MHS, FHRS, Brett D. Atwater, MD, James P. Daubert, MD, FHRS, Camille Frazier-Mills, MD, MHS, Donald D. Hegland, MD, Kevin P. Jackson, MD, Larry R. Jackson, MD, Jason I. Koontz, MD, PhD, Robert K. Lewis, MD, PhD, Sean D. Pokorney, MD, MBA, Albert Y. Sun, MD, Kevin L. Thomas, MD, Tristam D. Bahnson, MD, FHRS, Jonathan P. Piccini, MD, MHS, FHRS   +21 more
doaj   +1 more source

Picking the Locked Door

JACC: Case Reports, 2023
The management of atrial septal defects (ASDs) has been revolutionized by the advent of percutaneous transvenous occlusion devices. This case series describes techniques required to perform a transeptal puncture safely and effectively in patients ...
Noel Fitzpatrick, MB, MSc, John Keaney, MD, Edward Keelan, MB, Kevin P. Walsh, MD, Gábor Széplaki, PhD   +4 more
doaj   +1 more source

Effectiveness of catheter ablation of atrial fibrillation according to heart failure etiology

Journal of Arrhythmia, 2020
Background Catheter ablation is an important rhythm control therapy in patients with atrial fibrillation (AF) with concomitant heart failure (HF). The objective of this study was to assess the comparative efficacy of AF ablation patients with ischemic vs
Eric Black‐Maier, Benjamin A. Steinberg, Kevin M. Trulock, Frances Wang, Yuliya Lokhnygina, Wanda O'Neal, Sana Al‐Khatib, Brett D. Atwater, James P. Daubert, Camille Frazier‐Mills, Donald D. Hegland, Kevin P. Jackson, Larry R. Jackson, Jason I. Koontz, Robert K. Lewis, Albert Y. Sun, Kevin L. Thomas, Tristram D. Bahnson, Jonathan P. Piccini   +18 more
doaj   +1 more source

Autoimmune Atrial Fibrillation

Circulation, 2023
BACKGROUND: Atrial fibrillation (AF) is by far the most common cardiac arrhythmia. In about 3% of individuals, AF develops as a primary disorder without any identifiable trigger (idiopathic or historically termed lone AF). In line with the emerging field of autoantibody-related cardiac arrhythmias, the objective of this study ...
Maguy, Ange, Mahendran, Yuvaraj, Tardif, Jean-Claude, Busseuil, David, Li, Jin   +4 more
openaire   +5 more sources

Association of Sleep Duration With Atrial Fibrillation and Heart Failure: A Mendelian Randomization Analysis

Frontiers in Genetics, 2021
Both short (<7 h per night) and long (≥9 h per night) sleep durations are related to atrial fibrillation (AF) and heart failure (HF), but their causality has not been confirmed. We applied Mendelian randomization (MR) approaches to estimate the causal
Jianqiang Zhao, Fangkun Yang, Chengui Zhuo, Qiyue Wang, Zihao Qu, Qiqi Wang, Liangrong Zheng   +6 more
doaj   +1 more source

Physical Activity and Risks of Cardiovascular Diseases: A Mendelian Randomization Study

Frontiers in Cardiovascular Medicine, 2021
Background: Although some observational studies have shown that physical activity may have a positive relationship with cardiovascular diseases, the causal effect remains uncertain.
Chengui Zhuo, Jianqiang Zhao, Miao Chen, Yunlong Lu   +3 more
doaj   +1 more source

ABC of Atrial Fibrillation: DRUGS FOR ATRIAL FIBRILLATION [PDF]

BMJ, 1995
One of the most important principles of using antiarrhythmic drugs for controlling any arrhythmia is to treat only patients who are symptomatic, have malignant arrhythmias (such as ventricular fibrillation), or are haemodynamically compromised (for example, with hypotension or heart failure).
Shyam P Singh, Robert D S Watson, Gregory Y.H. Lip   +2 more
openaire   +3 more sources