Results 271 to 280 of about 98,834 (296)

Biomarkers Associated with Atrial Fibrosis and Remodeling

Current Medicinal Chemistry, 2019
Atrial fibrillation is the most common rhythm disturbance encountered in clinical practice. Although often considered as solely arrhythmic in nature, current evidence has established that atrial myopathy constitutes both the substrate and the outcome of atrial fibrillation, thus initiating a vicious, self-perpetuating cycle.
Polychronis, Dilaveris, Christos-Konstantinos, Antoniou, Panagiota, Manolakou, Eleftherios, Tsiamis, Konstantinos, Gatzoulis, Dimitris, Tousoulis   +5 more
openaire   +2 more sources

Hypercoagulability Promotes Atrial Fibrosis and Fibrillation

Blood, 2014
Abstract Background: It is well known that atrial fibrillation (AF) induces a hypercoagulable state, which significantly increases stroke risk in patients with AF contributing to morbidity and mortality in these patients. Active coagulation factors can also provoke diverse cellular responses through stimulation of protease-activated ...
Spronk, Henri M.H., De Jong, Anne-Margreet, De Boer, Hetty C., Maas, Alexander, Verheule, Sander, Rienstra, Michiel, Kamphuisen, Pieter W., Ten Cate, Hugo, Crijns, Harry J., Van Gelder, Isabelle, Van Zonneveld, Anton Jan, Schotten, Ullrich   +11 more
openaire   +2 more sources

Left Ventricular Fibrosis in Atrial Fibrillation

The American Journal of Cardiology, 2013
Excessive atrial fibrosis is involved in the pathogenesis of atrial fibrillation (AF), but little is known of left ventricular (LV) fibrotic status in patients with AF. In the present study, we investigated the presence of abnormal LV fibrosis in AF, its effect on cardiac function, a possible association with arterial stiffness (i.e., systemic ...
Eduard, Shantsila, Alena, Shantsila, Andrew D, Blann, Gregory Y H, Lip   +3 more
openaire   +2 more sources

BRD4 as a therapeutic target for atrial fibrosis and atrial fibrillation

European Journal of Pharmacology
This study aimed to elucidate the molecular mechanisms by which BRD4 play a role in atrial fibrillation (AF).We used a discovery-driven approach to detect BRD4 expression in the atria of patients with AF and in various murine models of atrial fibrosis.
Shuai Song, Jiali Yuan, Guojian Fang, Yingze Li, Shiao Ding, Yuepeng Wang, Qunshan Wang   +6 more
openaire   +2 more sources

Atrial Translocation of Porphyromonas gingivalis Exacerbates Atrial Fibrosis and Atrial Fibrillation

Circulation
BACKGROUND: Recent studies have indicated an association between periodontitis and atrial fibrillation (AF), although the underlying mechanisms remain unclear. Porphyromonas gingivalis (P ginigivalis ) is a causative agent of periodontal disease and is highly pathogenic.
Shunsuke Miyauchi, Miki Kawada-Matsuo, Hisako Furusho, Hiromi Nishi, Ayako Nakajima, Pham Trong Phat, Fumie Shiba, Masae Kitagawa, Kazuhisa Ouhara, Noboru Oda, Takehito Tokuyama, Yousaku Okubo, Sho Okamura, Taiichi Takasaki, Shinya Takahashi, Toru Hiyama, Hiroyuki Kawaguchi, Hitoshi Komatsuzawa, Mutsumi Miyauchi, Yukiko Nakano   +19 more
openaire   +2 more sources

Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation

Circulation Research, 2021
Stephan R Künzel, Maximilian Hoffmann, Mario Günscht   +2 more
exaly  

Implications of Inflammation and Fibrosis in Atrial Fibrillation Pathophysiology

Cardiac Electrophysiology Clinics, 2021

exaly  

The Human Atrial Fibrosis Pathway in the Development of Atrial Fibrillation

Cardiology, 2016
Adam S, Budzikowski, Granit, Veseli
openaire   +2 more sources

Acetyltransferase p300 regulates atrial fibroblast senescence and age‐related atrial fibrosis through p53/Smad3 axis

Aging Cell, 2023
Xiaoyan Gao, Meng-Zhen Zhang, Fang Rao   +2 more
exaly  

Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation

JACC: Clinical Electrophysiology, 2023
Shunsuke Miyauchi, Hiromi Nishi, Kazuhisa Ouhara, Takehito Tokuyama, Yousaku Okubo, Sho Okamura, Shogo Miyamoto, Naoto Oguri, Yukimi Uotani, Taiichi Takasaki, Keijiro Katayama, Hisako Furusho, Mutsumi Miyauchi, Shinya Takahashi, Toru Hiyama, Yukiko Nakano   +15 more
openaire   +1 more source