Results 81 to 90 of about 29,345 (146)

Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives

open access: yesEuropean Journal of Haematology, Volume 116, Issue 6, Page 759-770, June 2026.
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley   +1 more source

Prevalence and Characteristics of Cardiac Arrhythmia in Duchenne Muscular Dystrophy: A Retrospective, Single‐Center Holter Electrocardiographic Monitoring Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 6, June 2026.
In this retrospective single‐center study of 1018 routine Holter ECG recordings from 167 patients with Duchenne muscular dystrophy, nonsustained ventricular tachycardia and frequent premature ventricular complexes were common. Reduced left ventricular function was the strongest associated factor, supporting regular Holter monitoring for patients at ...
Ryo Sugiyama   +6 more
wiley   +1 more source

Exploring the Association Between Mental Disorders and Various Arrhythmias via Mendelian Randomization Methods

open access: yesGenes, Brain and Behavior, Volume 25, Issue 3, June 2026.
Based on the validity of instrumental variable assumptions, our Mendelian randomization analysis revealed that genetic predisposition to major depression was associated with an increased risk of arrhythmias and suggested potential bidirectional effects between major depression and atrioventricular block. ABSTRACT Major depression, bipolar disorder, and
Jingyang Su   +3 more
wiley   +1 more source

A Comprehensive Assessment of Renal Function During and After Pulsed Field Ablation

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 6, Page 1259-1267, June 2026.
ABSTRACT Background Acute kidney injury is an uncommon complication of pulsed field ablation (PFA). There is, however, limited empirical data on the dynamics of renal biomarkers apart from creatinine. Furthermore, no study to date has assessed creatinine at more than 24 h after the procedure. Methods Patients undergoing PFA for atrial fibrillation (AF)
Václav Melenovský   +10 more
wiley   +1 more source

Comparison of Integrated 3D Electroanatomic Mapping and Conventional Mapping Systems for Pentaspline Pulsed Field Ablation of Atrial Fibrillation

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 6, Page 1353-1355, June 2026.
ABSTRACT Introduction Pulsed field ablation (PFA) is an established therapy for atrial fibrillation (AF), yet optimal mapping strategies during pentaspline PFA remain uncertain. We compared procedural characteristics and material costs of an integrated 3D electroanatomic mapping (EAM) platform with conventional mapping systems. Methods and Results In a
Auroa Badin   +9 more
wiley   +1 more source

Poster Sessions

open access: yes
HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

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