Results 141 to 150 of about 19,328,196 (346)

Differential in inter-atrial dyssynchrony and atrial mechanical function in sick sinus syndrome with or without paroxysmal atrial fibrillation

, 2007
Objectives: To investigate the intra- and inter-atrial dyssynchrony in pts with sick sinus syndrome (SSS) combined with paroxysmal atrial fibrillation (PAF).
Wang, MM, Tse, HF, Lau, CP, Lee, KLF, Siu, DCW, Zhang, X   +5 more
core  

SynAtlas: A Safe and Versatile Platform for Rapid Organ‐Scale Tissue Clearing and 3D Atlas Mapping

Advanced Science, EarlyView.
An orthogonal synergy design principle integrates lipid solubilization, protein hydration modulation, and refractive‐index matching within a unified aqueous clearing system. This modular strategy enables rapid, low‐hazard, and broadly compatible tissue clearing while preserving molecular signals, supporting multiscale three‐dimensional imaging across ...
Mei‐Xue Yuan, Xin‐Ya Qin, Ling‐Jie Li, Kai‐Lang Xiao, Meng‐Meng Zhang, Kun‐Qi Chen, Peng Chen, Yu Wang, Chen‐Wei Wang, Nan Zhou, Qing‐Hong Shan   +10 more
wiley   +1 more source

Targeting a Calcium‐Associated Mitochondrial Vulnerability in TET2‐Deficient Myeloid Cells

Advanced Science, EarlyView.
Reduced TET2 function creates a calcium‐associated mitochondrial vulnerability in macrophages that is preferentially exploited by Lanatoside C. The resulting stress promotes apoptosis of TET2‐deficient macrophages, reduces inflammatory and fibrotic injury in human cardiac organoids, and highlights a genotype‐associated myeloid liability that may be ...
Yue Wang, Minh Duc Pham, Despina Stefanoska, Ting Yuan, Arka Provo Das, Chaonan Zhu, Meiqian Wu, Thanh Thuy Duong, Jaskiran Kaur, Yu Hao, Johannes Krefting, Marius Schwab, Jonathan Ward, Maria Duda, Wesley Abplanalp, Moritz von Scheidt, Andreas M. Zeiher, Stefanie Dimmeler, Jaya Krishnan   +18 more
wiley   +1 more source

Rare Differentiation in Genes XIRP1 and XIRP2 Associated With Hypertrophic Cardiomyopathy

AGING MEDICINE, EarlyView.
XIRP2, but not XIRP1, acts as a key genetic modifier in hypertrophic cardiomyopathy (HCM). Rare variants in XIRP2 are enriched in patients and lead to dramatic mRNA overexpression (> 9‐fold, p < 0.001). Functionally, this disrupts intercalated disc integrity.
Fang Wang, Tao Yuan, Wenna Zhao, Guili Shao, Shuping Li, Lingyan Lv, Rong Li, Jie Liu, Xiaoyun Li, Wennan Wang, Fusong Liu, Xingfu Shang, Song Hu   +12 more
wiley   +1 more source

Risk in Atrial Fibrillation: Left Atrial Function Matters [PDF]

European Journal of Heart Failure, 2019
Triposkiadis, F., Xanthopoulos, A., Parissis, J.   +2 more
openaire   +3 more sources

Non-alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes

, 2013
BackgroundThe relationship between non-alcoholic fatty liver disease (NAFLD) and atrial fibrillation (AF) in type 2 diabetes is currently unknown. We examined the relationship between NAFLD and risk of incident AF in people with type 2 diabetes.Methods ...
Zoppini Giacomo, S. Rodella, Filippo Valbusa, Mantovani William, Mantovani, W., BARBIERI, Enrico, Bertolini Lorenzo, ZOPPINI, Giacomo, L. Zenari, Byrne Christopher D., Zoppini, G., Giacomo Zoppini, Stefano Bonapace, Byrne, Christopher D., Stefano Rodella, Bertolini, L., CD Byrne, Bonapace Stefano, Giovanni Targher, L. Bertolini, Targher, G., Bonapace, S., Valbusa, F., Targher Giovanni, Christopher D Byrne, TARGHER, Giovanni, F. Valbusa, Barbieri, E., MANTOVANI, William, Barbieri Enrico, Rodella, S., Enrico Barbieri, Valbusa Filippo, Luciano Zenari, Zenari, L., William Mantovani, Rodella Stefano, Lorenzo Bertolini, Zenari Luciano, S. Bonapace   +39 more
core   +1 more source

Advances in HFpEF Research Based on Characteristics of Older Adults

AGING MEDICINE, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) in older adults is a systemic, age‐related syndrome involving cardiac, vascular, metabolic, and skeletal muscle dysfunction. The interconnected triad of frailty, sarcopenia, and malnutrition contributes to exercise intolerance, functional decline, and adverse clinical outcomes through inflammation,
Rui Li, Rosnani hashim
wiley   +1 more source

Lower left atrial function in young individuals with type 1 diabetes mellitus compared to healthy controls: an echocardiographic study

Scientific Reports
In adulthood, individuals with type 1 diabetes mellitus may develop a condition of heart failure with preserved ejection fraction. However, subclinical changes to the heart in diabetes are likely to occur prior to the clinical presentation.
Cecilia Fridolfsson, Johanna Thegerström, Karin Åkesson, Jan Engvall, Peter Blomstrand   +4 more
doaj   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Deep learning prediction of left atrial structure and function from 12-lead electrocardiograms

Nature Communications
Abnormal cardiac atrial structure and function, termed atrial cardiopathy, typically precedes atrial fibrillation and downstream cardiovascular complications, yet detection is limited by the cost and accessibility of high-quality cardiac imaging. Here we
Jennifer A. Brody, Vidhushei Yogeswaran, Kerri L. Wiggins, Colleen M. Sitlani, Joshua C. Bis, Lin Yee Chen, Susan R. Heckbert, João A. C. Lima, W. T. Longstreth, Bruce M. Psaty, Elsayed Z. Soliman, Geoffrey H. Tison, Ting Ye, Ali Shojaie, James S. Floyd   +14 more
doaj   +1 more source