Results 141 to 150 of about 85,886 (213)

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani   +5 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò   +18 more
wiley   +1 more source

Deficiencies in corin and atrial natriuretic peptide-mediated signaling impair endochondral ossification in bone development. [PDF]

open access: yesCommun Biol
Zhou Z   +10 more
europepmc   +1 more source

The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat. [PDF]

open access: yesFASEB J
Cherezova A   +12 more
europepmc   +1 more source

Cardiomyocyte‐Derived USP20 Attenuates Diabetic Cardiomyopathy by Facilitating the Degradation of STING and Mitigating STING‐Mediated Inflammation

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
USP20 directly binds to STING and promotes the degradation of STING through the autophagy pathway by deubiquitinating p62 via its active site C154, thereby alleviating myocardial inflammation and improving ventricular remodeling and heart failure induced by diabetes. ABSTRACT Although extensive clinical and basic research has been conducted on diabetic
Yixin Zhou   +15 more
wiley   +1 more source

Predictive Value of Midregional Pro-Atrial Natriuretic Peptide for Cardioembolic Stroke in Hyperacute Ischemic Stroke. [PDF]

open access: yesJ Am Heart Assoc
Ikenouchi H   +12 more
europepmc   +1 more source

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