The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson +22 more
wiley +1 more source
Subacute Bioprosthetic Mitral Valve and Inter-Atrial Septum Mural Thrombosis. [PDF]
Wang PP +4 more
europepmc +1 more source
OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang +12 more
wiley +1 more source
Short-term effect of low atrial septum pacing on new-onset atrial fibrillation in patients with sinus node dysfunction a prospective randomized single-center study. [PDF]
Wu Y, Tu X, Jin Q, Zheng J, Gao Z.
europepmc +1 more source
Giant Papillary Fibroelastoma Attached to the Left Atrial Septum, Near the Foramen Ovale. [PDF]
Tsugu T +3 more
europepmc +1 more source
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot +4 more
wiley +1 more source
Outcomes of Adults With Unrepaired Partial Anomalous Pulmonary Venous Return and Intact Atrial Septum. [PDF]
Egbe AC +7 more
europepmc +1 more source
Commentary: Hypoplastic left heart syndrome with intact atrial septum: Planning for success. [PDF]
Burkhart HM, Mir A, Schwartz RM.
europepmc +1 more source
Successful preoperative bridge with extracorporeal membrane oxygenation in three neonates with D-transposition of the great vessels and pulmonary hypertension [PDF]
Gazit, Avihu Z +2 more
core +1 more source

