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Hypoplastic left heart syndrome [PDF]

Orphanet Journal of Rare Diseases, 2007
Hypoplastic left heart syndrome(HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left
Thiagarajan Ravi, Connor Jean
doaj   +5 more sources

Hypoplastic Left Heart Syndrome: A Case Report

Journal of Nepal Medical Association, 2023
Hypoplastic left heart syndrome is a rare critical congenital heart defect constituting a prevalence of 1/3,500 to 1/12,500 live births in which there is obstructions to the blood flow within the left heart.
Sunil Raja Manandhar, Anjila Ghimire, Dipendra Rai, Sabina Shrestha, Pritha Adhikari   +4 more
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What Is the Hypoplastic Left Heart Syndrome?

Journal of Cardiovascular Development and Disease, 2023
As yet, there is no agreed definition for the so-called “hypoplastic left heart syndrome”. Even its origin remains contentious. Noonan and Nadas, who as far as we can establish first grouped together patients as belonging to a “syndrome” in 1958 ...
Robert H. Anderson, Adrian Crucean, Diane E. Spicer   +2 more
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Impact of Left Ventricular Morphology on Adverse Outcomes Following Stage 1 Palliation for Hypoplastic Left Heart Syndrome: 20 Years of National Data From Sweden

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Hypoplastic left heart syndrome is associated with significant morbidity and mortality. We aimed to assess the influence of left ventricular morphology and choice of shunt on adverse outcome in patients with hypoplastic left heart syndrome and
Katrin Fricke, Mats Mellander, Katarina Hanséus, Phan‐Kiet Tran, Mats Synnergren, Jens Johansson Ramgren, Annika Rydberg, Jan Sunnegårdh, Magnus Dalén, Gunnar Sjöberg, Constance G. Weismann, Petru Liuba,   +11 more
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Hypoplastic Left Heart Syndrome: Is There a Role for Fetal Therapy?

Frontiers in Pediatrics, 2022
During fetal life some cardiac defects may lead to diminished left heart growth and to the evolution of a form of hypoplastic left heart syndrome (HLHS).
Andreas Tulzer, Andreas Tulzer, James C. Huhta, Julian Hochpoechler, Kathrin Holzer, Thomas Karas, David Kielmayer, Gerald Tulzer   +7 more
doaj   +3 more sources

The Left Ventricular Myocardium in Hypoplastic Left Heart Syndrome

Journal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is a collective term applied to severe congenital cardiac malformations, characterised by a combination of abnormalities mainly affecting the left ventricle, associated valves, and ascending aorta.
Bill Chaudhry, Ahlam Alqahtani, Lorraine Eley, Louise Coats, Corina Moldovan, Srinivas R. Annavarapu, Deborah J. Henderson   +6 more
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Hypoplastic left heart syndrome with mitral regurgitation: a new marker of poor fetal outcome [PDF]

Journal of Ultrasonography
Hypoplastic left heart syndrome is a severe congenital heart defect that may be accompanied by tricuspid and mitral valve regurgitation. The aim of this paper is to identify a new ultrasound marker for evaluating the outcomes of fetuses with hypoplastic ...
Witkowski Sławomir, Respondek-Liberska Maria, Strzelecka Iwona   +2 more
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A rare case of hypoplastic left heart syndrome in pregnancy and its outcome [PDF]

New Indian Journal of OBGYN, 2022
Hypoplastic left heart syndrome is abnormal development of left sided cardiac structure, leading to obstruction to blood flow from the left ventricular outflow tract.
Akshatha DS, Shakuntala PN, Sreelatha S, Sumayya, Shruthi   +4 more
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Transcriptome studies of congenital heart diseases: identifying current gaps and therapeutic frontiers

Frontiers in Genetics, 2023
Congenital heart disease (CHD) are genetically complex and comprise a wide range of structural defects that often predispose to - early heart failure, a common cause of neonatal morbidity and mortality.
Nkechi Martina Odogwu, Clinton Hagen, Timothy J. Nelson, Timothy J. Nelson, Timothy J. Nelson, Timothy J. Nelson, Timothy J. Nelson   +6 more
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Use of Frogs as a Model to Study the Etiology of HLHS

Journal of Cardiovascular Development and Disease, 2023
A frog is a classical model organism used to uncover processes and regulations of early vertebrate development, including heart development. Recently, we showed that a frog also represents a useful model to study a rare human congenital heart disease ...
Shuyi Nie
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