Results 31 to 40 of about 4,157,661 (176)

Hypoplastic Left Heart Syndrome: About a Postnatal Death

open access: yesDiagnostics, 2023
Background: Hypoplastic left heart syndrome (HLHS) is a congenital heart disease that is associated with high mortality rates in the early neonatal period and during surgical treatments. This is mainly due to missed prenatal diagnosis, delayed diagnostic
Pasquale Giugliano   +6 more
doaj   +1 more source

Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome

open access: yesJournal of Cardiovascular Development and Disease, 2022
Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single systemic ...
Angela N. Baybayon-Grandgeorge   +3 more
doaj   +1 more source

Hypoplastic left heart syndrome

open access: yes, 2009
Hypoplastic left heart syndrome is a rare congenital heart defect in which the left side of the heart is underdeveloped. Surgical management of hypoplastic left heart syndrome has changed the prognosis of the condition that was previously regarded as ...
Wright, John   +5 more
core   +1 more source

Creation of high position fetal balloon atrial septoplasty for hypoplastic left heart syndrome and highly restrictive atrial septum: A case report and literature review

open access: yesJournal of Interventional Medicine, 2020
Background: Fetal balloon atrial septoplasty (BAS) is performed through the restrictive foramen ovale in fetal cases with established hypoplastic left heart syndrome (HLHS) and an intact or highly restrictive atrial septum (RAS).
Ai Zhang   +4 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Hypoplastic Left Heart Syndrome

open access: yes, 2003
Despite approximately 50 years of progress in the management of com­ plex congenital heart disease, hypoplastic left heart syndrome (HLHS) has been one of the last cardiac malformations to yield to effective surgical treat­ ment.
Rychik, Jack, Wernovsky, Gil
core   +1 more source

Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections

open access: yesStem Cell Research & Therapy
Background Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function.
Carlos Gallego-Navarro   +10 more
doaj   +1 more source

Hypoplastic left heart syndrome

open access: yes, 2018
Hypoplastic left heart syndrome surgery in neonates has revolutionized survival in childhood. A new population with complex univentricular circulations has been created. Complex management problems can be anticipated for the adult survivors.
Alessandro Giardini
core   +1 more source

Pleural and mediastinal effusions after the extracardiac total cavopulmonary connection: Risk factors and impact on outcome

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundThis study investigated the volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection, as well as preoperative risk factors and their impact on outcome.Materials and methodsA total of 210 ...
Paul Philipp Heinisch   +17 more
doaj   +1 more source

Facilitating the timely diagnosis of Lennox–Gastaut syndrome: A checklist to support clinical practice

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To develop and evaluate a simple‐to‐use checklist to support physicians with the timely diagnosis of Lennox–Gastaut syndrome (LGS). Methods A panel of 10 pediatric and adult epileptologists used the International League Against Epilepsy (ILAE) criteria for LGS classification and definition to develop seven questions for the checklist,
Nicola Specchio   +9 more
wiley   +1 more source

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