Results 11 to 20 of about 4,157,661 (176)

Left-Sided Heart Defects and Laterality Disturbance in Hypoplastic Left Heart Syndrome

open access: yesJournal of Cardiovascular Development and Disease, 2023
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by hypoplasia of left-sided heart structures. The developmental basis for restriction of defects to the left side of the heart in HLHS remains unexplained.
Hisato Yagi, Cecilia W. Lo
doaj   +2 more sources

Hypoplastic left heart syndrome: a review [PDF]

open access: yesActa Medica Lituanica, 2016
Background. Hypoplastic left heart syndrome (HLHS) is an etiologically multifactorial congenital heart disease affecting one in 5,000 newborns. Thirty years ago there were no treatment options for this pathology and the  natural course of the  disease ...
Roberts Gobergs   +2 more
doaj   +2 more sources

Whole Genome Sequencing in Hypoplastic Left Heart Syndrome

open access: yesJournal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome ...
Jeanne L. Theis, Timothy M. Olson
doaj   +2 more sources

Hypoplastic left heart syndrome – Unresolved Issues [PDF]

open access: yesFrontiers in Pediatrics, 2014
Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present it is expected that - at best - 70% of newborns with HLHA will reach adulthood. This review addresses the problems of right ventricular failure and
Raoul Roman Arnold   +2 more
doaj   +2 more sources

Tricuspid Valve Hemangioma Associated with Hypoplastic Left Heart Syndrome Presenting as Sudden Infant Death Syndrome [PDF]

open access: yesTürk Patoloji Dergisi, 2019
Primary cardiac tumors are rare in children with a low incidence varying from 0.0017 to 0.28% in autopsy studies. Approximately 90% of the reported primary cardiac tumors in the pediatric population are benign and the most common subtype is rhabdomyomas ...
Brijnandan GUPTA   +4 more
doaj   +2 more sources

Considering the Genetic Architecture of Hypoplastic Left Heart Syndrome [PDF]

open access: yesJournal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is among the most severe cardiovascular malformations and understanding its causes is crucial to making progress in prevention and treatment.
John W. Belmont
doaj   +2 more sources

Resource and cost considerations in treating hypoplastic left heart syndrome

open access: yesPediatric Health, Medicine and Therapeutics, 2016
Miguel Urencio,1 Chris Greenleaf,1 Jorge D Salazar,2 Ali Dodge-Khatami2 1Division of Cardiothoracic Surgery, 2Children’s Heart Center, University of Mississippi Medical Center, Jackson, MS, USA Abstract: Hypoplastic left heart syndrome (HLHS) was a
Urencio M   +3 more
doaj   +1 more source

Fetal hypoplastic left heart syndrome: key factors shaping prognosis

open access: yesJournal of Perinatal Medicine
The purpose of the study is to estimate factors affecting survival in prenatally diagnosed hypoplastic left heart syndrome (HLHS) and echocardiographic features predicting poor prognosis and early neonatal death.
Cambaztepe Büşra   +4 more
doaj   +2 more sources

Facets of parenting a child with hypoplastic left heart syndrome [PDF]

open access: yes, 2012
The purpose of the study was to conceptualize the needs of parents of young children with hypoplastic left heart syndrome (HLHS) to provide a theoretical framework to informthe development of future parent interventions.
Rogers, L.G.   +3 more
core   +1 more source

Decreased left heart flow in fetal lambs causes left heart hypoplasia and pro-fibrotic tissue remodeling

open access: yesCommunications Biology, 2023
Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic left heart syndrome (HLHS). To investigate if a decrease in left heart flow results in growth failure, we generate left ventricular inflow obstruction (LVIO ...
Miriam S. Reuter   +13 more
doaj   +1 more source

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