Results 21 to 30 of about 16,514 (185)

First report of hypoplastic left heart syndrome in 3p- syndrome and review of candidate genes [PDF]

Revista Paulista de Pediatria
Objective: 3p deletion syndrome is a rare monosomal disease that encompasses deletions throughout the short arm of chromosome 3. It is often in the distal region (3p25-pter), but variations in breakpoints and a complex clinical manifestation exist, with ...
Ana Kalise Böttcher, Monique Banik Siqueira, Natasha Malgarezi, Marcela Rodrigues Nunes, Rafaella Mergener, Luisa Pigatto Kalil, Patrícia Trevisan, Paulo Ricardo Gazzola Zen   +7 more
doaj   +1 more source

Whole Genome Sequencing in Hypoplastic Left Heart Syndrome

Journal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome ...
Jeanne L. Theis, Timothy M. Olson
doaj   +1 more source

Reports of 2 Rare Associations of Hypoplastic Left Heart Syndrome

JACC: Case Reports, 2019
This report describes 2 contrasting yet rare associations of hypoplastic left heart syndrome, 1 in a patient with pulmonary valve stenosis that was successfully surgically palliated and the other in a patient with an intact atrial septum and stenotic ...
K. Anitha Jayakumar, MD, Gouri Tilak, MD, Bibhuti B. Das, MD   +2 more
doaj   +1 more source

Hypoplastic Left Heart Syndrome: About a Postnatal Death

Diagnostics, 2023
Background: Hypoplastic left heart syndrome (HLHS) is a congenital heart disease that is associated with high mortality rates in the early neonatal period and during surgical treatments. This is mainly due to missed prenatal diagnosis, delayed diagnostic
Pasquale Giugliano, Paola Ciamarra, Mariavictoria De Simone, Alessandro Feola, Pierluca Zangani, Carlo Pietro Campobasso, Gelsomina Mansueto   +6 more
doaj   +1 more source

Mechanical tricuspid valve replacement in hypoplastic left heart syndrome: An institutional experienceCentral MessagePerspective

JTCVS Open, 2022
Objective: Atrioventricular valvar regurgitation in patients with single ventricles is associated with worse outcomes. Valve repair or replacement has been undertaken in an attempt to reduce mortality and morbidity.
Mehar Hoda, MD, Robert Douglas Benjamin Jaquiss, MD, Lorraine James, MD, Poonam Punjwani Thankavel, MD   +3 more
doaj   +1 more source

Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome

Journal of Cardiovascular Development and Disease, 2022
Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single systemic ...
Angela N. Baybayon-Grandgeorge, Ashley E. Pietra, Shelley D. Miyamoto, Anastacia M. Garcia   +3 more
doaj   +1 more source

Creation of high position fetal balloon atrial septoplasty for hypoplastic left heart syndrome and highly restrictive atrial septum: A case report and literature review

Journal of Interventional Medicine, 2020
Background: Fetal balloon atrial septoplasty (BAS) is performed through the restrictive foramen ovale in fetal cases with established hypoplastic left heart syndrome (HLHS) and an intact or highly restrictive atrial septum (RAS).
Ai Zhang, Gang Luo, Yue Sun, Taotao Chen, Silin Pan   +4 more
doaj   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections

Stem Cell Research & Therapy
Background Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function.
Carlos Gallego-Navarro, James Jaggers, Harold M. Burkhart, Waldemar F. Carlo, David L. Morales, M. Yasir Qureshi, Joseph W. Rossano, Clinton E. Hagen, Drew K. Seisler, Susana Cantero Peral, Timothy J. Nelson   +10 more
doaj   +1 more source

Tricuspid Valve Hemangioma Associated with Hypoplastic Left Heart Syndrome Presenting as Sudden Infant Death Syndrome

Türk Patoloji Dergisi, 2019
Primary cardiac tumors are rare in children with a low incidence varying from 0.0017 to 0.28% in autopsy studies. Approximately 90% of the reported primary cardiac tumors in the pediatric population are benign and the most common subtype is rhabdomyomas ...
Brijnandan GUPTA, Shouriyo GHOSH, Maikal KUJUR, Khushbu KHETAN, Tarun KUMAR   +4 more
doaj   +1 more source