Results 51 to 60 of about 59,480 (283)
Whole Genome Sequencing in Hypoplastic Left Heart Syndrome
Journal of Cardiovascular Development and Disease, 2022 Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome ...
Jeanne L. Theis, Timothy M. Olson
doaj +1 more source
Near-infrared spectroscopy after high-risk congenital heart surgery in the paediatric intensive care unit [PDF]
, 2011 Objective: To establish whether the use of near-infrared spectroscopy is potentially beneficial in high-risk cardiac infants in United Kingdom paediatric intensive care units. Design: A prospective observational pilot study.
Hovarth +5 more
core +1 more source
First report of hypoplastic left heart syndrome in 3p- syndrome and review of candidate genes [PDF]
Revista Paulista de PediatriaObjective: 3p deletion syndrome is a rare monosomal disease that encompasses deletions throughout the short arm of chromosome 3. It is often in the distal region (3p25-pter), but variations in breakpoints and a complex clinical manifestation exist, with ...
Ana Kalise Böttcher +7 more
doaj +1 more source
Hypoplastic Left Heart Syndrome: About a Postnatal Death
Diagnostics, 2023 Background: Hypoplastic left heart syndrome (HLHS) is a congenital heart disease that is associated with high mortality rates in the early neonatal period and during surgical treatments. This is mainly due to missed prenatal diagnosis, delayed diagnostic
Pasquale Giugliano +6 more
doaj +1 more source
Reports of 2 Rare Associations of Hypoplastic Left Heart Syndrome
JACC: Case Reports, 2019 This report describes 2 contrasting yet rare associations of hypoplastic left heart syndrome, 1 in a patient with pulmonary valve stenosis that was successfully surgically palliated and the other in a patient with an intact atrial septum and stenotic ...
K. Anitha Jayakumar, MD +2 more
doaj +1 more source
JTCVS Open, 2022 Objective: Atrioventricular valvar regurgitation in patients with single ventricles is associated with worse outcomes. Valve repair or replacement has been undertaken in an attempt to reduce mortality and morbidity.
Mehar Hoda, MD +3 more
doaj +1 more source
Health Expectations, 2020 To explore the role of antenatal counselling in how parents make treatment decisions following an antenatal diagnosis of Hypoplastic Left Heart Syndrome (HLHS).
S. Bertaud +4 more
semanticscholar +1 more source
Medical Therapies for Heart Failure in Hypoplastic Left Heart Syndrome
Journal of Cardiovascular Development and Disease, 2022 Significant surgical and medical advances over the past several decades have resulted in a growing number of infants and children surviving with hypoplastic left heart syndrome (HLHS) and other congenital heart defects associated with a single systemic ...
Angela N. Baybayon-Grandgeorge +3 more
doaj +1 more source
A randomised trial of early palliative care for maternal stress in infants prenatally diagnosed with single-ventricle heart disease [PDF]
, 2018 Children with single-ventricle disease experience high mortality and complex care. In other life-limiting childhood illnesses, paediatric palliative care may mitigate maternal stress.
Aiyagari, Ranjit +10 more
core +2 more sources
Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease?
Journal of Cardiovascular Development and Disease, 2019 Hypoplastic left heart syndrome occurs in up to 3% of all infants born with congenital heart disease and is a leading cause of death in this population. Although there is strong evidence for a genetic component, a specific genetic cause is only known in ...
P. Grossfeld +4 more
semanticscholar +1 more source