Results 61 to 70 of about 59,480 (283)

Survival, Neurocognitive, and Functional Outcomes After Completion of Staged Surgical Palliation in a Cohort of Patients With Hypoplastic Left Heart Syndrome

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Management of patients with hypoplastic left heart syndrome has benefited from advancements in medical and surgical care. Outcomes have improved, although survival and long‐term functional and cognitive deficits remain a concern.
J. Atallah, G. Garcia Guerra, A. Joffe, Gwen Bond, S. Islam, M. Ricci, M. Alaklabi, I. Rebeyka, C. Robertson   +8 more
semanticscholar   +1 more source

Age- and Lesion-Related Comorbidity Burden Among US Adults With Congenital Heart Disease: A Population-Based Study. [PDF]

, 2019
Background As patients with congenital heart disease (CHD) are living longer, understanding the comorbidities they develop as they age is increasingly important.
Agarwal, Anushree, Broberg, Craig S, Dudley, R Adams, Foster, Elyse, Harris, Ian S, John, Anitha, Mahadevan, Vaikom S, Marcus, Greg M, Thombley, Robert, Vittinghoff, Eric   +9 more
core   +1 more source

Creation of high position fetal balloon atrial septoplasty for hypoplastic left heart syndrome and highly restrictive atrial septum: A case report and literature review

Journal of Interventional Medicine, 2020
Background: Fetal balloon atrial septoplasty (BAS) is performed through the restrictive foramen ovale in fetal cases with established hypoplastic left heart syndrome (HLHS) and an intact or highly restrictive atrial septum (RAS).
Ai Zhang, Gang Luo, Yue Sun, Taotao Chen, Silin Pan   +4 more
doaj   +1 more source

Autologous stem cell therapy for hypoplastic left heart syndrome: Safety and feasibility of intraoperative intramyocardial injections.

Journal of Thoracic and Cardiovascular Surgery, 2019
OBJECTIVES Staged surgical palliation for hypoplastic left heart syndrome results in an increased workload on the right ventricle serving as the systemic ventricle.
H. Burkhart, M. Qureshi, J. Rossano, Susana Cantero Peral, P. O’Leary, M. Hathcock, W. Kremers, Timothy J. Nelson   +7 more
semanticscholar   +1 more source

Pleural and mediastinal effusions after the extracardiac total cavopulmonary connection: Risk factors and impact on outcome

Frontiers in Cardiovascular Medicine, 2022
BackgroundThis study investigated the volume and duration of pleural and mediastinal effusions following extracardiac total cavopulmonary connection, as well as preoperative risk factors and their impact on outcome.Materials and methodsA total of 210 ...
Paul Philipp Heinisch, Paul Philipp Heinisch, Paul Metz, Paul Metz, Helena Staehler, Helena Staehler, Benedikt Mayr, Janez Vodiskar, Janez Vodiskar, Martina Strbad, Martina Strbad, Bettina Ruf, Peter Ewert, Alfred Hager, Jürgen Hörer, Jürgen Hörer, Masamichi Ono, Masamichi Ono   +17 more
doaj   +1 more source

Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: The European Association for Cardio-Thoracic Surgery (EACTS) and the Association for European Paediatric and Congenital Cardiology (AEPC) Hypoplastic Left Heart Syndrome Guidelines Task Force.

European Journal of Cardio-Thoracic Surgery, 2020
The IPCCC is a standardized international system of paediatric and congenital cardiac nomenclature that should be used in all registries, databases and research studies in the domain of paediatric and congenital cardiac care, including those related to ...
N. Alphonso, A. Angelini, D. Barron, H. Bellsham-Revell, N. Blom, K. Brown, D. Davis, Daniel R. Duncan, M. Fedrigo, L. Galletti, D. Hehir, U. Herberg, J. Jacobs, K. Januszewska, T. Karl, E. Malec, B. Maruszewski, J. Montgomerie, Christian Pizzaro, D. Schranz, A. Shillingford, J. Simpson   +21 more
semanticscholar   +1 more source

Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. [PDF]

, 2020
Genetic variants are the primary driver of congenital heart disease (CHD) pathogenesis. However, our ability to identify causative variants is limited.
Bernstein, Daniel, Bisgrove, Brent W, Brueckner, Martina, Chung, Wendy K, Deanfield, John, Demarest, Bradley, Edwards, Jonathan J, Fernandez, Nicolas F, Gelb, Bruce D, Giardini, Alessandro, Goldmuntz, Elizabeth, Kim, Richard, Lachmann, Alexander, Lifton, Richard P, Ma'ayan, Avi, Newburger, Jane W, Porter, George, Roberts, Amy E, Rouillard, Andrew D, Seidman, Christine E, Shankaran, Sunita S, Srivastava, Deepak, Tristani-Firouzi, Martin, Turan, Nahid, Wang, Zichen, Yost, H Joseph   +25 more
core  

Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy. [PDF]

, 2017
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease ...
A Cevik, A Correa-Villasenor, A deAlmeida, A Granger, A Kulkarni, AP Vlahos, C Scholz, Carlin S Long, CL Antos, D Sedmera, DD Lemon, DJ Cao, Douglas D Lemon, J Lu, JP Cardinale, JW Newburger, JW Rossano, JW Rossano, Karin Nunley, Katharina M Lutter, KB Schuetze, Kimberly M Demos-Davies, KM Demos-Davies, M Tanno, MA Cavasin, MA Cavasin, Maria A Cavasin, MP Gupta, OA O'Connor, PA Marks, PC Frommelt, Q Yang, R Kirk, RG Ohye, S Chen, Sam Payne, SD Miyamoto, SD Miyamoto, SD Miyamoto, Shelley D Miyamoto, SJ Nakano, SK Mani, SM Williams, TA McKinsey, TG Gillette, Timothy A McKinsey, VM Klimek, Weston W Blakeslee, WJ Kowalski, WW Blakeslee   +49 more
core   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source

Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections

Stem Cell Research & Therapy
Background Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function.
Carlos Gallego-Navarro, James Jaggers, Harold M. Burkhart, Waldemar F. Carlo, David L. Morales, M. Yasir Qureshi, Joseph W. Rossano, Clinton E. Hagen, Drew K. Seisler, Susana Cantero Peral, Timothy J. Nelson   +10 more
doaj   +1 more source