Results 241 to 250 of about 40,978 (301)

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

Small, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long, Jinpeng Sun, Dongli Zhou, Can Chen, Jiangcheng Shu, Xiaobo Mao, Kunwu Yu, Minglu Liang, Long Chen, Yumei Wang, Min Cheng   +10 more
wiley   +1 more source

Prenatal diagnosis and postnatal management of perinatal thoracoabdominopelvic tumors: multicenter experience

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives The primary objective was to assess the accuracy of prenatal examination in detecting and characterizing perinatal solid tumors of the thoracoabdominopelvic region. Secondary objectives were to describe the epidemiology, clinical characteristics and outcome of these tumors.
C. Khawand, D. Orbach, D. Berrebi, S. Branchereau, C. Mussini, H. J. Brisse, D. Grévent, J.‐M. Jouannic, A. Vivanti, V. Minard‐Colin, Y. Ville, S. Sarnacki, Collaborators, S. Moalla, H. Boutroux, S. Irtan, S. Boudjemaa, P. Philippe‐Chomette, D. Luton, J. Rosenblatt, T. Quibel, F. Guimiot, N. Roux, J. Martinovic   +23 more
wiley   +1 more source

Effect of Cardiac Rehabilitation on Cardiovascular Events in Patients With Advanced Chronic Kidney Disease

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Little is known about the effect of cardiac rehabilitation (CR) on cardiovascular events in patients with advanced chronic kidney disease (CKD). Methods We performed a retrospective cohort study in 189 patients with an estimated glomerular filtration rate of less than 30 mL/min/1.73 m2 who were referred to our outpatient CR center.
Tomoaki Hama, Takatoshi Kakuta, Kazushige Amano, Akiko Ushijima, Fuminobu Yoshimachi, Yuji Ikari   +5 more
wiley   +1 more source

Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals

Integrative Zoology, EarlyView.
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley   +1 more source

Cardiac function and coronary plaque development following masculinizing gender‐affirming hormone therapy: A prospective cohort study

Andrology, EarlyView.
Abstract Introduction Myocardial dysfunction and the presence of calcified and non‐calcified coronary plaques are predictors of cardiovascular disease. Masculinizing gender‐affirming hormone therapy may increase cardiovascular risk, highlighting the need for prospective studies to evaluate cardiovascular outcomes during gender‐affirming hormone therapy.
Laust Frisenberg Buhl, Marianne S. Andersen, Jan Frystyk, Axel Diederichsen, Selma Hasific, Rikke Hjortebjerg, Jordi Sanchez Dahl, Manijeh Noori, Kirstine Nørregaard Hansen, Gitte Maria Jørgensen, Camilla Viola Palm, Tine Taulbjerg Kristensen, Dorte Glintborg, Louise Lehmann Christensen   +13 more
wiley   +1 more source

Influence of Preoperative Anatomical Characteristics on the Direction of Inflow Cannula in HeartMate 3

Artificial Organs, EarlyView.
The IC direction in HM3 was influenced by the mitral valve height from the LV apex, distance between the LV apex and chest wall, and thoracic depth from the LV apex. Moreover, the IC direction in HM3 had little influence on the flow, PAWP and the survival rate of patients.
Shusuke Imaoka, Daisuke Yoshioka, Shunsuke Saito, Takuji Kawamura, Ai Kawamura, Ryohei Matsuura, Yusuke Misumi, Koichi Toda, Shigeru Miyagawa   +8 more
wiley   +1 more source

Physiological Control of Realheart Total Artificial Heart

Artificial Organs, EarlyView.
This study evaluates the Realheart Total Artificial Heart's preload‐based physiological controller, which dynamically adjusts heart rate and stroke volume to mimic the heart's natural responses during sleep, rest, and exercise using a hybrid mock circulation loop of the cardiovascular system.
Emanuele Perra, Daniel Jonasson, Shaikh Faisal Zaman, Nils Brynedal Ignell, Michael Broomé, Thomas Finocchiaro, Ina Laura Perkins, Seraina Anne Dual   +7 more
wiley   +1 more source

Nationwide Danish Register Based Study Showed a Stable Prevalence of Congenital Diaphragmatic Hernias From 1994 to 2021 but a Decrease in Syndromic Cases

Acta Paediatrica, EarlyView.
ABSTRACT Aim Congenital diaphragmatic hernia (CDH) is a severe malformation with high morbidity and mortality. This Danish study evaluated the birth prevalence, co‐occurring malformations, and temporal trends of CDH over nearly three decades. Methods Nationwide data from the Danish Biobank Register were used to identify liveborn infants diagnosed with ...
Ulrik Lausten‐Thomsen, Paula L. Hedley, Kristin M. Conway, Katrine M. Løfberg, Lars S. Johansen, Paul A. Romitti, Michael Christiansen   +6 more
wiley   +1 more source

Chylothorax after patent ductus arteriosus ligation in a dog with persistent left cranial vena cava

Australian Veterinary Journal, EarlyView.
This report is the first to document chylothorax after patent ductus arteriosus (PDA) ligation in a dog with a persistent left cranial vena cava (PLCVC), highlighting potential complications arising from concurrent cardiovascular anomalies. A nine‐month‐old female desexed Pomeranian was referred for PDA. Echocardiography confirmed a left‐to‐right shunt
TR Nash, GL Hosgood
wiley   +1 more source

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou, Jun Xia, Yingjuan Liu, Wenqi He, Hongyuan Zhang, Bernard D. Keavney, Min Zi, Binh Y. Nguyen, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Susanne S. Hille, Elizabeth J. Cartwright, Oliver J. Müller, Honglin Xu, Sam Butterworth, Xin Wang   +16 more
wiley   +1 more source