Results 21 to 30 of about 461,644 (99)

The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation [PDF]

, 2005
Background— The molecular mechanism of increased background inward rectifier current (IK1) in atrial fibrillation (AF) is not fully understood. We tested whether constitutively active acetylcholine (ACh)-activated IK,ACh contributes to enhanced basal ...
Ravens, U., Wettwer, E., Christ, T., Voigt, N., Friedrich, A., Knaut, M., Jost, Norbert, Dobrev, D.   +7 more
core   +1 more source

Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation [PDF]

, 2007
5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT₄ receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown.
Kane, K.A., Kane, Kathleen A., Rankin, A.C., Workman, Antony J., Pau, Davide, Workman, A.J., Rankin, Andrew C., Pau, D.   +7 more
core   +1 more source

D-Transposition of great arteries with severe calcific aortic stenosis in an adult patient: a rare presentation

Polish Journal of Thoracic and Cardiovascular Surgery, 2022
The incidence of transposition of great arteries (TGA) is 31 per 100000 live births worldwide [1]. It is, however, the most common cyanotic congenital heart defect seen in neonates [2].
Prashant Mishra, Kuntal Surana, Chaitanya Raut, Vijay Shewale   +3 more
doaj   +1 more source

Late Onset Postcapillary Pulmonary Hypertension in Patients With Transposition of the Great Arteries and Mustard or Senning Baffles

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThere is a paucity of data regarding late‐onset pulmonary hypertension (PH) in patients with transposition of the great arteries and atrial switch surgery.
Marie‐A. Chaix, Annie Dore, Lise‐Andrée Mercier, François‐Pierre Mongeon, François Marcotte, Réda Ibrahim, Anita W. Asgar, Azadeh Shohoudi, Fabien Labombarda, Blandine Mondésert, Nancy Poirier, Paul Khairy   +11 more
doaj   +1 more source

Surgery for transposition of great arteries: A historical perspective

Annals of Pediatric Cardiology, 2015
The history of surgery for transposition of great arteries (TGA) has paralleled the history of cardiac surgery. In fact, it began before the birth of open heart surgery when the palliative Blalock-Hanlon septectomy was first performed in 1948. The atrial
Supreet P Marathe, Sachin Talwar
doaj   +1 more source

Circulating annexin A5 levels after atrial switch for transposition of the great arteries: relationship with ventricular deformation and geometry. [PDF]

PLoS ONE, 2012
BACKGROUND: Inflammatory cytokines, cardiomyocyte apoptosis, and altered collagen turnover may contribute to unfavourable ventricular remodeling. This unfavourable ventricular remodelling is well documented in patients after atrial switch operation for ...
Clare T M Lai, Pak-cheong Chow, Sophia J Wong, Koon-wing Chan, Yiu-fai Cheung   +4 more
doaj   +1 more source

Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRV Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Heart failure is the leading cause of death in adults with a systemic right ventricle (sRV). While dapagliflozin has proven benefits in patients with acquired heart diseases and heart failure with reduced ejection fraction, its impact remains ...
Mathieu Albertini, Victor Waldmann, Pauline David, Alexis Barat, Antoine Legendre, Anne‐Solene Chaussade, Laurence Iserin, Magalie Ladouceur   +7 more
doaj   +1 more source

Atrial cellular electrophysiological changes in patients with ventricular dysfunction may predispose to AF [PDF]

, 2009
<b>Background:</b> Left ventricular systolic dysfunction (LVSD) is a risk factor for atrial fibrillation (AF), but the atrial cellular electrophysiological mechanisms in humans are unclear.
Marshall, G.E., Kane, K.A., Redpath, C.J., Redpath, C., Platonov, Pyotr, Russell, J.A., Rankin, A.C., Norrie, J., Workman, A.J., Pau, D., Platonov, Pyotr,, Lund University.   +11 more
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Double left atrial appendage: A diagnostic dilemma

Annals of Pediatric Cardiology, 2023
We report a unique intraoperative finding of an additional double left atrial appendage (LAA) during an arterial switch operation with ventricular septal defect closure in a 4-month-old girl.
Nilanjan Dutta, Debasis Das, Unmesh Chakraborty, Shubhadeep Das, Manish Kumar Sharma, Shivani Gajpal, Amitabha Chattopadhyay, Sanjiban Ghosh, Jayita Nandy Das   +8 more
doaj   +1 more source

Role of the liver in splanchnic extraction of atrial natriuretic factor in the rat [PDF]

, 1992
Mesenteric, hepatic and splanchnic extraction of C-terminal and N-terminal atrial natriuretic factor was investigated in male Sprague-Dawley rats. Plasma concentrations (mean ± S.E.M.) of C-terminal atrial natriuretic factor were 55.0 ± 6.1 fmol/ml, 31.2
Dieter Jungst, Witthaut, Rochus, Thibault, Gaétan, Manfred Bilzer, Alexander L. Gerbes, Jüngst, Dieter, Gülberg, Veit, Bilzer, Manfred, Gerbes, Alexander L., L Veit Gulberg, Rochus Witthaut, Gaétan Thibault, Veit Gülberg   +12 more
core   +1 more source