Results 41 to 50 of about 461,644 (99)

Transient outward K+ current (ITO) reduction prolongs action potentials and promotes afterdepolarisations: a dynamic-clamp study in human and rabbit cardiac atrial myocytes [PDF]

, 2012
Background and aim: Human atrial transient outward K+ current (ITO) is decreased in a variety of cardiac pathologies, but how ITO reduction alters action potentials (AP) and arrhythmia mechanisms is poorly understood, owing to non-selectivity of ITO ...
Marshall, G.E., Dempster, J., Smith, G.L., Rankin, A.C., Workman, A.J.   +4 more
core   +1 more source

Neonatal intra-atrial baffle repair for isolated ventricular inversion with left isomerism: a case report

Surgical Case Reports, 2020
Background Discordant atrioventricular connection with concordant ventriculoarterial connection, otherwise known as isolated ventricular inversion (IVI), is an extremely rare congenital cardiac malformation.
Yuta Kuwahara, Yukihiro Takahashi, Yuya Komori, Naohiro Kabuto, Naoki Wada   +4 more
doaj   +1 more source

Pregnancy Outcomes in Women After Arterial Switch Operation for Transposition of the Great Arteries: Results From ROPAC (Registry of Pregnancy and Cardiac Disease) of the European Society of Cardiology EURObservational Research Programme

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In the past 3 decades, the arterial switch procedure has replaced the atrial switch procedure as treatment of choice for transposition of the great arteries.
Oktay Tutarel, Karishma P. Ramlakhan, Lucia Baris, Maria T. Subirana, Judith Bouchardy, Attila Nemes, Niels G. Vejlstrup, Olga A. Osipova, Mark R. Johnson, Roger Hall, Jolien W. Roos‐Hesselink   +10 more
doaj   +1 more source

Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade [PDF]

, 2011
Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K+ currents.
Currie, S., Tellez, James O, Julie A. Russell, Kane, Kathleen A, Jhund, Pardeep S, Boyett, M.R., Rankin, A.C., Pardeep S. Jhund, Mark R. Boyett, Dempster, John, Marshall, Gillian E., John Dempster, Currie, Susan, Russell, J.A., Workman, Antony J., Marshall, Gillian E, Workman, A.J., Marshall, G.E., Russell, Julie A, Dempster, J., Rankin, Andrew C, Russell, Julie A., Gillian E. Marshall, Tellez, James O., Boyett, Mark R, Kathleen A. Kane, Boyett, Mark R., Andrew C. Rankin, Rankin, Andrew C., Kane, K.A., Workman, Antony J, Tellez, J.O., Antony J. Workman, Kane, Kathleen A., Jhund, P.S., Susan Currie, James O. Tellez, Jhund, Pardeep S.   +37 more
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Oral anticoagulant switching in patients with atrial fibrillation: a scoping review

BMJ Open, 2023
Introduction Oral anticoagulants (OACs) prevent stroke in patients with atrial fibrillation (AF). Several factors may cause OAC switching.Objectives To examine the phenomenon of OAC switching in patients with AF, including all available evidence ...
Mary A De Vera, Kimberlyn McGrail, Peter S Loewen, Adenike R Adelakun, Ricky D Turgeon   +4 more
doaj   +1 more source

The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation [PDF]

, 2001
<b>Objective:</b> To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of accompanying ion current changes.
K Shivkumar, Kane, K.A., Kane, Kathleen, Rankin, A.C., A Workman, Workman, A.J.   +5 more
core   +1 more source

Atrial natriuretic factor [PDF]

, 1987
The discovery of the first well-defined natriuretic hormone, the Atrial Natriuretic Factor (ANF), has prompted research on its impact on volume regulation in health and disease.
Arendt, Rainer M., Paumgartner, Gustav, Morris, Mariana, Gerbes, Alexander L., Buckalew, V M, Hamilton, R W   +5 more
core   +1 more source

Longitudinal strain by two-dimensional speckle tracking to assess ventricular function in adults with transposition of the great arteries: Can serial assessment be simplified?

Revista Portuguesa de Cardiologia, 2018
Introduction: Transposition of the great arteries (TGA) is a rare form of congenital heart disease in which most patients reach adulthood. Right ventricular dysfunction is the most severe residual complication in long-term follow-up, both in patients ...
Ana T. Timóteo, Luísa M. Branco, Sílvia A. Rosa, Ana Galrinho, Lídia Sousa, José A. Oliveira, Maria F. Pinto, Ana F. Agapito, Rui C. Ferreira   +8 more
doaj   +1 more source

Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety Analysis [PDF]

, 2009
Background: A recent trial unexpectedly reported that atrial fibrillation, when defined as serious, occurred more often in participants randomized to an annual infusion of the relatively new parenteral bisphosphonate, zoledronic acid, than among those ...
Aroon Hingorani, Douglas, I, Hingorani, A, Douglas, Ian, MacAllister, Raymond, Grosso, Anthony, MacAllister, R, Anthony Grosso, Liam Smeeth, Smeeth, Liam, Raymond MacAllister, Grosso, A, Smeeth, L, Ian Douglas, Hingorani, Aroon   +14 more
core   +1 more source

External Validation of a Risk Score Model for Predicting Major Clinical Events in Adults After Atrial Switch

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background A risk model has been proposed to provide a patient individualized estimation of risk for major clinical events (heart failure events, ventricular arrhythmia, all‐cause mortality) in patients with transposition of the great arteries and atrial
Mathieu Albertini, Beatrice Santens, Flavia Fusco, Berardo Sarubbi, Pastora Gallego, Maria‐Jose Rodriguez‐Puras, Katja Prokselj, Robert Martijn Kauling, Jolien Roos‐Hesselink, Fabien Labombarda, Alexander Van De Bruaene, Werner Budts, Victor Waldmann, Laurence Iserin, Odilia Woudstra, Berto Bouma, Magalie Ladouceur   +16 more
doaj   +1 more source