Results 121 to 130 of about 71,583 (333)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

Diagnosis and treatment of recurrent syncope in a middle‐aged women

open access: yesAnnals of Noninvasive Electrocardiology
A 50‐year‐old female patient, presented with repeated syncope for more than 2 years. Prior assessments were conducted at different hospitals, but no definite abnormalities were found.
Wenyi He, Xin Fu, Xinyue Du, Guolan Deng
doaj   +1 more source

Experimental atrioventricular block without thoracotomy: a new instrument [PDF]

open access: yes, 2017
Experimental permanent total atrioventricular block was produced by a simplified method, without thoracotomy, by one person, and without the aid of x-ray apparatus.
Babotai, I., Brownlee, R.
core  

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

open access: yesClinical Genetics, EarlyView.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson   +22 more
wiley   +1 more source

Electrocardiography in horses, part 2: how to read the equine ECG [PDF]

open access: yes, 2010
The equine practitioner is faced with a wide variety of dysrhythmias, of which some are physiological. The recording of an exercise electrocardiogram (ECG) can help distinguish between physiological and pathological dysrhythmias, underlining the ...
De Clercq, Dominique   +5 more
core  

Machine learning‐based prediction of atrial fibrillation in patients with atrial high‐rate episodes

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background Given the modest performance of available predictive models in estimating the risk of atrial fibrillation (AF) in patients with atrial high‐rate episodes (AHREs) detected by cardiac implantable electronic devices (CIEDs), this study explores the potential use of machine learning (ML) algorithms in this context. Purpose To assess the
Amir Askarinejad   +9 more
wiley   +1 more source

Central nervous system involvement in cardiac amyloidosis: Redefining the heart‐brain axis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Central nervous system involvement in cardiac amyloidosis. Amyloidosis is a systemic disease that can directly affect the central nervous system. Furthermore, the amyloid cardiomyopathy can indirectly affect the central nervous system by inducing systemic hypoperfusion and increasing the risk of acute ischaemic stroke.
Domenico Mario Giamundo   +3 more
wiley   +1 more source

Hodgkin lymphoma as a rare cause of complete atrioventricular block: a case report

open access: yesКардиоСоматика
INTRODUCTION: Complete atrioventricular block is a life-threatening condition that requires urgent intervention and pacemaker implantation. Determining the underlying cause of the block is essential for effective management. This article describes a rare
Ekaterina A. Pravkina   +4 more
doaj   +1 more source

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