Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo +5 more
wiley +1 more source
Not only Van Gogh: a case of BRASH syndrome with concomitant digoxin toxicity
Background Bradycardia, renal failure, atrioventricular (AV) node blocking, shock, and hyperkalemia syndrome is a potentially life-threatening clinical condition characterized by bradycardia, renal failure, atrioventricular (AV) node blocking, shock, and
Ilaria Costantini +8 more
doaj +1 more source
High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
A Atkinson +49 more
core +1 more source
Abstract figure legend Integrated multimodal platform for panoramic cardiac mapping in isolated heart experiments. On the left, an image of the experimental setup during data acquisition showing a Langendorff‐perfused rabbit heart surrounded by three optical cameras (CAM A, B and C) positioned 120° apart, each coupled with high‐power LEDs for panoramic
Jimena Siles +8 more
wiley +1 more source
Catheter ablation of an accessory pathway and atrioventricular node modification using 550 kHz radiofrequency was attempted in 23 children and adolescents between five and 19 years of age (mean = 15.7 years). Fifteen children had accessory-pathway-
A Celiker, P Brugada
doaj
Predictive factors of atrioventricular conduction disorders [PDF]
Atrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently,
Carmen Marina Deutsch +2 more
doaj +1 more source
Repolarization adaptation to rapid change in heart rate in human models – a review
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt +5 more
wiley +1 more source
Complete Heart Block Lacking Functional Anatomical Impairment in the Conduction System
Introduction: Complete heart block also known as third-degree atrioventricular block (AV block) is a condition in which there is no conduction of the impulse produce in the sinoatrial node (SA node) in the atrium to the ventricle.1 Complete heart ...
Shazia Yasir, Komal Owais, Ishratullah
doaj
Diastolic And Systolic Right Ventricular Dysfunction Precedes Left Ventricular Dysfunction In Patients Paced From Right Ventricular Apex [PDF]
Background: Cardiac dysfunction after right ventricular (RV) apical pacing is well known but its extent, time frame of appearance and individual effect on left ventricular (LV), RV systolic and diastolic parameters has not evaluated in a systematic ...
Bansal, Sandeep +7 more
core
Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. [PDF]
The origin of sinoatrial node (SAN) pacemaker activity in the heart is controversial. The leading candidates are diastolic depolarization by "funny" current (If) through HCN4 channels (the "Membrane Clock" hypothesis), depolarization by cardiac Na-Ca ...
Alber, Sarah +13 more
core +2 more sources

