Results 71 to 80 of about 35,622 (245)

HCN4 in the atrioventricular node

Heart Rhythm
Hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) drives the funny current in cardiac pacemaker regions. Its involvement in sinoatrial node pacemaker generation is well known, but its function in the atrioventricular (AV) node (AVN) has not intensively been studied.
Jaël S. Copier, Arie O. Verkerk, Elisabeth M. Lodder   +2 more
openaire   +2 more sources

Self‐Administered Etripamil Nasal Spray Slows Ventricular Rate in Patients With Atrial Fibrillation: A Post Hoc Analysis of the NODE‐303 Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Currently, there are no available fast‐acting agents to control the ventricular rate (VR) during atrial fibrillation (AF) episodes that can be self‐administered by patients on an as‐needed basis without medical supervision. Here, we aim to evaluate the effect of intranasal etripamil on VR in patients treating presumed paroxysmal ...
Paul Dorian, Marco Alings, Benoit Coutu, James E. Ip, Felipe A. Martinez, Jonathan P. Piccini, Bruce S. Stambler, Muhammad Sheikh, Silvia Shardonofsky, David B. Bharucha, A. John Camm   +10 more
wiley   +1 more source

Feasibility and Efficacy of His Bundle Pacing or Left Bundle Pacing Combined With Atrioventricular Node Ablation in Patients With Persistent Atrial Fibrillation and Implantable Cardioverter‐Defibrillator Therapy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Persistent atrial fibrillation may lead to a higher probability of inappropriate shocks in heart failure patients with an implantable cardioverter‐defibrillator (ICD). The aim of this study was to evaluate the impact of His‐Purkinje conduction
Songjie Wang, Shengjie Wu, Lei Xu, Fangyi Xiao, Zachary I. Whinnett, Pugazhendhi Vijayaraman, Lan Su, Weijian Huang   +7 more
doaj   +1 more source

The Underscreening of Cardiac Amyloidosis in Patients With Pacemakers—A Single Centre Retrospective Audit

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Cardiac amyloidosis is commonly associated with cardiac conduction disease. We sought to determine the prevalence of advanced conduction disease requiring a pacemaker in patients with known cardiac amyloidosis to evaluate current screening practices among patients receiving pacemakers.
Peishan Cai, Timothy Scully, Jason Nogic, Kah Peck, Jithin Sajeev   +4 more
wiley   +1 more source

Frequency-dependent anti arrhythmic effects of crataegus monogyna on the extracellular field potential recordings in the rabbit atrioventricular node, an experimental model of AF [PDF]

, 2011
Introduction: Despite extensive studies that have been performed on the effects of Crataegus monogyna in cardiovascular diseases, only few investigations have addressed the antiarrhythmic properties of this plant.
Alizadeh, A.M., Azadbakht, M., Badaghabadi, F., Changizi, S., Jamshidi, A.H., Khori, V., Nayebpour, M., Pourabouk, M., Rajaei, M.   +8 more
core  

Shortening of the Short Refractory Periods in Short QT Syndrome. [PDF]

, 2017
BACKGROUND: Diagnosis of short QT syndrome (SQTS) remains difficult in case of borderline QT values as often found in normal populations. Whether some shortening of refractory periods (RP) may help in differentiating SQTS from normal subjects is unknown.
Cardin, C, Fourcade, C, Gaita, F, Gandjbakhch, E, Giustetto, C, Maupain, C, Maury, P, Mondoly, P, Monteil, B, Rollin, A, Scrocco, C   +10 more
core   +3 more sources

Atrioventricular node ablation and His bundle pacing [PDF]

EP Europace, 2017
Atrioventricular node ablation (AVNA) and right ventricular pacing (RVP) are effective therapies for patients with atrial fibrillation (AF) and rapid ventricular rates. His bundle pacing (HBP) is a physiologic alternative to RVP. The aim of our study is to assess the feasibility and safety of HBP in patients undergoing AVNA and its effect on left ...
Pugazhendhi, Vijayaraman, Faiz A, Subzposh, Angela, Naperkowski   +2 more
openaire   +2 more sources

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundClinical benefits from His bundle pacing (HBP) in heart failure patients with preserved and reduced left ventricular ejection fraction are still inconclusive.
Weijian Huang, Lan Su, Shengjie Wu, Lei Xu, Fangyi Xiao, Xiaohong Zhou, Kenneth A. Ellenbogen   +6 more
doaj   +1 more source