Results 71 to 80 of about 23,461 (251)

Premature Ventricular Contractions From the Proximal Left Anterior Fascicle: Insight From the Electrophysiologic and Anatomic Parameters

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Premature ventricular contractions (PVCs) originating from the proximal left anterior fascicle (LAF) are rarely discussed. We aimed to describe the characteristics and ablation outcome of PVCs originating from the proximal LAF and propose a stepwise approach.
Xuan Hoang Le, Chin Yu Lin, Fa Po Chung, Yenn Jiang Lin, Shih Lin Chang, Li Wei Lo, Yu Feng Hu, Ta Chuan Tuan, Tze Fan Chao, Jo Nan Liao, Guan Yi Li, Ting Yung Chang, Ling Kuo, Cheng I. Wu, Chih Min Liu, Shin Huei Liu, Ming Jen Kuo, Yu‐Shan Huang, Lo Chieh Ling, Cheng Han Chan, Da Wei Chang, Minh Nhut Nguyen, Paula Victoria Catherine Cheng Bromeo, Shih Ann Chen   +23 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Electrophysiological differences of randomized deep sedation with dexmedetomidine versus propofol

BMC Anesthesiology
Background Dexmedetomidine and propofol are common sedatives in intensive care units and for interventional procedures. Both may compromise sinus node function and atrioventricular conduction.
Helge Servatius, Thomas Kueffer, Gabor Erdoes, Jens Seiler, Hildegard Tanner, Fabian Noti, Andreas Haeberlin, Antonio Madaffari, Mattia Branca, Sophie Dütschler, Lorenz Theiler, Tobias Reichlin, Laurent Roten   +12 more
doaj   +1 more source

Fundamentals of System Design for Cardiac Pulsed Field Ablation: Optimization of Safety, Efficacy, and Usability

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT The goal of a cardiac pulsed field ablation (PFA) system is to provide safe, effective, and usable therapy for the treatment of cardiac arrhythmias. Achieving this goal is a complex exercise in system design, requiring optimization of catheter, waveform, and dosing. This optimization is often iterative, as myriad design factors are balanced to
Brendan Koop
wiley   +1 more source

Surgical and Electrical Anatomy of the Inter-Nodal and Intra-Atrial Conduction System in the Heart

Journal of Chest Surgery, 2022
An anatomical understanding of the atrial myocardium is crucial for surgeons and interventionists who treat atrial arrhythmias. We reviewed the anatomy of the inter-nodal and intra-atrial conduction systems.
Jeong-Wook Seo, Jung-Sun Kim, Myung-Jin Cha, Ja Kyoung Yoon, Min-Ju Kim, Hsuan-Ming Tsao, Chang-Ha Lee, Seil Oh   +7 more
doaj   +1 more source

Atrial fibrillation, sinoatrial and atrioventricular node dysfunction in a mouse model of heart failure with preserved ejection fraction

Experimental Physiology, EarlyView.
Summary of the timeline of characterized events related to atrial fibrilation (AF) and diastolic dysfunction in a mouse heart failure with preserved ejection fraction (HFpEF) model. Three weeks after the initiation of the diet regimen with high fat diet (HFD) and Nω‐nitro‐l‐arginine methyl ester (l‐NAME) in drinking water to induce HFpEF, significantly
Bernadin Ndongson‐Dongmo, Reinhard Bauer, Finn Olav Levy   +2 more
wiley   +1 more source

Cystic tumour of the atrioventricular node: case report and literature review

Forensic Sciences Research, 2019
Cystic tumour of the atrioventricular node is the smallest tumour that can cause sudden cardiac death. This lesion arises from foregut endodermal rests which become enfolded into the heart during embryogenesis.
Stephen D. Cohle
doaj   +1 more source

Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits

Experimental Physiology, EarlyView.
Abstract Glycogen storage disease III (GSD‐III) is caused by an inherited deficiency of the glycogen debranching enzyme. Affecting the liver, muscle and heart, GSD‐IIIa is the most common GSD‐III subtype. We evaluated the feasibility and safety of a physical exercise intervention in patients with GSD‐IIIa and its effects at the multisystem level.
Asunción Bustos‐Sellers, Almudena Montalvo‐Pérez, Araceli Boraita, Gonzalo Saco‐Ledo, Lidia B. Alejo, David Barranco‐Gil, Pedro L. Valenzuela, Nerea López‐Maldonado, Roser Ferrer‐Costa, Javier Esparcia‐Estrela, Celia Monteagudo‐López, Tomàs Pinós, Alejando Santos‐Lozano, Alejandro Lucia, Alfredo Santalla   +14 more
wiley   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

Experimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson, Man Si, Krystle Trosclair, Ellen Aughenbaugh, Maxine Parkinson, Nicole M. Gautier‐Hall, Megan Watts, Frederica Kizek, Md. Shenuarin Bhuiyan, Paari Dominic, Kathryn A. Hamilton, Edward Glasscock   +11 more
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source