Results 81 to 90 of about 36,622 (316)

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Clinical and Electrophysiological Predictors of Ventriculoatrial Conduction in Patients under Evaluation for Ventricular Tachyarrhythmia

Journal of Tehran University Heart Center, 2010
Background: Ventriculoatrial (VA) conduction has an important role in the initiation and maintenance of some arrhythmias. The aim of this study was to evaluate whether clinical and electrophysiological parameters of atrioventricular (AV) conduction can ...
Mohammad Reza Dehghani, Azam Soleimani, Mohammad Reza Samiei Nasab   +2 more
doaj  

How to read the equine electrocardiogram? : tips and tricks [PDF]

, 2011
C
van Loon, Gunther
core   +1 more source

Isorhythmic atrioventricular dissociation during anaesthesia in a cat

Veterinary Record Case Reports, EarlyView.
Abstract A 10‐year‐old, male, neutered domestic shorthair cat with suspected hypertrophic cardiomyopathy was referred for cystotomy to remove uroliths present in its urinary bladder. Fifteen minutes after induction of general anaesthesia, atrioventricular dissociation was noted on the electrocardiogram with similar atrial and ventricular firing rates ...
Gemma Padrosa Sala, Cristian Cabellos Clemente, Paul Wotton, Frane Ivasovic   +3 more
wiley   +1 more source

Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

Aging Cell, EarlyView.
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibit cystic regions, immune cell infiltration, early osteoblast differentiation and increased regurgitation.
Laura Bevan, Jessica Radford, Helena Urquijo, Joseph Carr, Alice Etheridge, Stephen Cross, Melanie Hezzell, Rebecca J. Richardson   +7 more
wiley   +1 more source

Electrophysiological differences of randomized deep sedation with dexmedetomidine versus propofol

BMC Anesthesiology
Background Dexmedetomidine and propofol are common sedatives in intensive care units and for interventional procedures. Both may compromise sinus node function and atrioventricular conduction.
Helge Servatius, Thomas Kueffer, Gabor Erdoes, Jens Seiler, Hildegard Tanner, Fabian Noti, Andreas Haeberlin, Antonio Madaffari, Mattia Branca, Sophie Dütschler, Lorenz Theiler, Tobias Reichlin, Laurent Roten   +12 more
doaj   +1 more source

Automatic Mode Switching in Atrial Fibrillation [PDF]

, 2005
Automatic mode switching (AMS) algorithms were designed to prevent tracking of atrial tachyarrhythmias (ATA) or other rapidly occurring signals sensed by atrial channels, thereby reducing the adverse hemodynamic and symptomatic consequences of a rapid ...
Antonio De, Simone, Enrico, Romano, Giuseppe, Stabile   +2 more
core  

Ionic basis of a differential effect of adenosine on refractoriness in rabbit AV nodal and atrial isolated myocytes [PDF]

, 1999
Methods: The whole cell patch clamp technique was used to record action potentials and ion currents in AV nodal and left atrial myocytes isolated enzymatically from rabbit hearts.
Kane, K.A., Rankin, A.C., Workman, A.J.
core   +1 more source