Abstract Objective To understand differences in thyroid hormone replacement therapy with levo‐thyroxine (l‐T4) between acquired and congenital hypothyroid (CH) patients. Design We compared biochemical thyroid parameters between euthyroid subjects (EU) and both CH adult patients and thyroidectomized patients (TP) under replacement therapy.
Marco Russo+5 more
wiley +1 more source
Split Knockoffs for Multiple Comparisons: Controlling the Directional False Discovery Rate [PDF]
Multiple comparisons in hypothesis testing often encounter structural constraints in various applications. For instance, in structural Magnetic Resonance Imaging for Alzheimer's Disease, the focus extends beyond examining atrophic brain regions to include comparisons of anatomically adjacent regions.
arxiv +1 more source
Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Derakhshan, M.H.+10 more
core +1 more source
Abstract Hepatitis B, caused by the hepatitis B virus (HBV), is a global public health issue that affects 290 million people worldwide. Most people with hepatitis B are in low‐ and middle‐income countries (LMIC), where health systems and resources are often constrained.
Caroline Lee+2 more
wiley +1 more source
Interleukin-17A promotes parietal cell atrophy by inducing apoptosis [PDF]
Background & Aims: Atrophic gastritis caused by chronic inflammation in the gastric mucosa leads to the loss of gastric glandular cells, including acid-secreting parietal cells.
Alderuccio+47 more
core +3 more sources
Association of Long Non-Coding RNA Polymorphisms with Gastric Cancer and Atrophic Gastritis
Long non-coding RNAs (lncRNA) play an important role in the carcinogenesis of various tumours, including gastric cancer. This study aimed to assess the associations of lncRNA ANRIL, H19, MALAT1, MEG3, HOTAIR single-nucleotide polymorphisms (SNPs) with ...
V. Petkevicius+7 more
semanticscholar +1 more source
Diagnostic values of serum levels of pepsinogens and gastrin-17 for screening gastritis and gastric cancer in a high risk area in Northern Iran [PDF]
Background: Gastric cancer (GC) is the second cause of cancer related death in the world. It may develop by progression from its precancerous condition, called gastric atrophy (GA) due to gastritis.
Ahmadi, A.+7 more
core +1 more source
Is Screening for and Surveillance of Atrophic Gastritis Advisable? [PDF]
Gastric cancer remains a leading cause of cancer-related deaths in many parts of the world. At present, prevention seems to be the most effective means to reduce its the incidence and mortality rate. Gastric atrophy is considered the first relevant step in the histogenesis of gastric adenocarcinoma.
NARDONE, GERARDO ANTONIO PIO+7 more
openaire +4 more sources
Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S.+7 more
core +2 more sources
Objectives: We aimed to determine serum PGs (serum pepsinogens) and H. Pylori IgG in atrophic gastritis and gastric cancer patients and evaluate the gastric cancer risk.
Ganchimeg Dondov+9 more
doaj +1 more source