Results 61 to 70 of about 3,949 (160)

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Once‐Daily and Proactive Twice‐Weekly Roflumilast Cream 0.05% for Mild‐to‐Moderate Atopic Dermatitis in Children Aged 2–5 Years From a 52‐Week, Phase 3 Trial (INTEGUMENT‐OLE)

Pediatric Dermatology, Volume 43, Issue 3, Page 642-649, May/June 2026.
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield, Mercedes E. Gonzalez, Mark Boguniewicz, Tracy Funk, Adelaide A. Hebert, Vimal H. Prajapati, Chesahna Kindred, Rocco Serrao, Lisa Swanson, David Krupa, Scott Snyder, Melissa S. Seal, Diane Hanna, Patrick Burnett, David R. Berk   +14 more
wiley   +1 more source

Signaling Cascades of Pasteurella multocida Toxin in Immune Evasion

Toxins, 2013
Pasteurella multocida toxin (PMT) is a protein toxin found in toxigenic strains of Pasteurella multocida. PMT is the causative agent for atrophic rhinitis in pigs, a disease characterized by loss of nasal turbinate bones due to an inhibition of ...
Bianca Kloos, Katharina F. Kubatzky, Dagmar Hildebrand   +2 more
doaj   +1 more source

Empty nose syndrome: etiopathogenesis and management

The Egyptian Journal of Otolaryngology, 2016
Empty nose syndrome (ENS) is an iatrogenic disorder most often recognized by the presence of paradoxical nasal obstruction despite an objectively wide patent nasal cavity.
Magdy Eisa Saafan, Hassan Moustafa Hegazy, Osama A. Albirmawy   +2 more
doaj   +1 more source

Surgical and Regenerative Treatment Options for Empty Nose Syndrome: A Systematic Review [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives Patients with empty nose syndrome typically experience paradoxical nasal congestion, nasal dryness, epistaxis, and suffocation. Conservative management is generally preferred for empty nose syndrome.
Do Hyun Kim, Mohammed Abdullah Basurrah, Soo Whan Kim, Sung Won Kim   +3 more
doaj   +1 more source

[Research status and prospect of tissue engineering technology in treatment of atrophic rhinitis]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2023
Lei S, Hu J, Tang Y, Gan W, Song Y, Jiang Y, Zhang H, Gao Y, Yang H, Xie H.   +9 more
europepmc   +1 more source

Nasal myiasis in clinical practice

Apollo Medicine, 2018
Nasal myiasis is an opportunistic parasitic infestation of human as well as animals. Infestation of the nasal cavity by dipterous larvae is called nasal myiasis which is commonly seen in developing countries where health and sanitation are poor ...
Santosh Kumar Swain, Mahesh Chandra Sahu, Manash Ranjan Baisakh,   +3 more
doaj   +1 more source

Exploring the Mechanism of Yiqi Qingre Ziyin Method in Regulating Neuropeptide Expression for the Treatment of Atrophic Rhinitis. [PDF]

Dis Markers, 2022
Lu L, Kang X, Yi B, Jiang C, Yan X, Chen B, Sun Y, Shi F, Luo Y, Chen Y, Shi R.   +10 more
europepmc   +1 more source

An Updated Review on Atrophic Rhinitis and Empty Nose Syndrome

Ear, Nose & Throat Journal
Objective: Atrophic rhinitis (AR) is a rare clinical condition affecting the nasal mucosa. It is characterized by progressive nasal congestion and thick, bothersome nasal secretions. In this narrative review, pathogenesis, differences between the 2 types
Ibrahim Ali Sumaily MBBS, SB, KSUF, Nouf Adel Hakami MBBS, Anwar Dhawi Almutairi MBBS, Abdulrahman Abdullah Alsudays MBBS, Ebrahim Mohammed Abulqusim MBBS, Mohammed Maki Abualgasem MBBS, Abdulrahman Ahmad Alghulikah MBBS, SB, Abdulrahman Awad Alserhani MBBS, SB   +7 more
doaj   +1 more source

Characteristics of the blood plasma “lipid peroxidation — antioxidant protection” system depending on nasal mucosa microflora composition in various chronic rhinitis phenotypes

Инфекция и иммунитет
Chronic rhinitis is the most common ENT disease. Over the past decade, there has been an increased incidence of chronic rhinitis. In all forms of chronic rhinitis, there is a decrease in the protective properties of nasal mucous membrane, which can be ...
O. V. Smirnova, N. S. Goncharova
doaj   +1 more source