Results 1 to 10 of about 346,071 (293)

Nasal symbiont Staphylococcus epidermidis restricts the cellular entry of influenza virus into the nasal epithelium

npj Biofilms and Microbiomes, 2022
Our recent study presented that human nasal commensal Staphylococcus epidermidis could potentiate antiviral immunity in the nasal mucosa through interferon-related innate responses. Here, we found that human nasal commensal S.
Ara Jo, Jina Won, Chan Hee Gil, Su Keun Kim, Kang-Mu Lee, Sang Sun Yoon, Hyun Jik Kim   +6 more
doaj   +1 more source

Nasal Delivery of High Molecular Weight Drugs

Molecules, 2009
Nasal drug delivery may be used for either local or systemic effects. Low molecular weight drugs with are rapidly absorbed through nasal mucosa. The main reasons for this are the high permeability, fairly wide absorption area, porous and thin endothelial
Erdal Cevher, Yıldız Ozsoy, Sevgi Gungor   +2 more
doaj   +1 more source

Symbiotic microbiome Staphylococcus epidermidis restricts IL-33 production in allergic nasal epithelium via limiting the cellular necroptosis

BMC Microbiology, 2023
Background Allergic rhinitis (AR) is characterized by airway inflammation in nasal mucosa from inhaled allergens and interleukin (IL)-33 is the potent inducer of Th2 inflammation in allergic nasal epithelium. Staphylococcus epidermidis is one of the most
Yung Jin Jeon, Chan Hee Gil, Jina Won, Ara Jo, Hyun Jik Kim   +4 more
doaj   +1 more source

Cold bubble humidification of low-flow oxygen does not prevent acute changes in inflammation and oxidative stress at nasal mucosa

Scientific Reports, 2021
Some clinical situations require the use of oxygen therapy for a few hours without hypoxemia. However, there are no literature reports on the effects of acute oxygen therapy on the nasal mucosa.
Lauriana Alves Santana, Suellen Karoline Moreira Bezerra, Beatriz Mangueira Saraiva-Romanholo, Wellington Pereira Yamaguti, Iolanda de Fátima Lopes Calvo Tibério, Tabata Maruyama dos Santos, Renato Fraga Righetti   +6 more
doaj   +1 more source

Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats

Allergology International, 2006
Background: Histamine synthesized by histidine decarboxylase (HDC) from L-histidine is a major chemical mediator in the development of nasal allergy which is characterized by nasal hypersensitivity. However the regulatory mechanism of histamine synthesis
Yoshiaki Kitamura, Asish K Das, Yuki Murata, Kazutaka Maeyama, Shrabanti Dev, Yousuke Wakayama, Bukasa Kalubi, Noriaki Takeda, Hiroyuki Fukui   +8 more
doaj   +1 more source

Prevalence of fungal biofilms in patients with nasal polyposis: a systematic review [PDF]

Reviews in Clinical Medicine, 2016
Introduction: There are many internal and external factors that are considered as the main causes of nasal infections and inflammation in chronic rhinosinusitis (CRS) leading to polyposis.
Navid Nourizadeh, Akram Adabizadeh
doaj   +1 more source

Cytokines, Proliferation Markers, Antimicrobial Factors and Neuropeptide-Containing Innervation in Human Nasal Mucosa after Rhinoseptoplasty Procedure

Medical Sciences, 2021
The nasal cavity lined by nasal mucosa, is a significant part of respiratory system of human. However, there are no studies aimed to detect a molecular phenotype of healthy and normal functioning nasal mucosa, obtained after rhinoseptoplasty procedure ...
Marija Podlesnaja, Mara Pilmane, Gunta Sumeraga   +2 more
doaj   +1 more source

CHRONIC NASAL HYPER-REACTIVITY (CURRENT CLASSIFICATIONS, CLINICAL PATTERN, DIAGNOSIS)

Медицинский совет, 2017
Nasal hyper-reactivity (NG) is a clinical phenomenon manifested by increased individual sensitivity of the nasal mucosa to factors that do not cause symptoms in healthy people.
E. P. MERKULOVA, S. N. KOLESNIKOVA
doaj   +1 more source

Intranasal Delivery of a Chitosan-Hydrogel Vaccine Generates Nasal Tissue Resident Memory CD8⁺ T Cells That Are Protective against Influenza Virus Infection

Vaccines, 2020
Rapid antigen clearance from the nasal mucosa is one of the major challenges in the development of intranasal vaccines. Here, we tested whether intranasal immunization with a chitosan-hydrogel vaccine, with in situ gelling properties, extended antigen ...
James G. Bedford, Irina Caminschi, Linda M. Wakim   +2 more
doaj   +1 more source

TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis

Allergology International, 2010
: Background: Transforming growth factor-p (TGF-β) levels are elevated in the nasal mucosa in allergic rhinitis. However, because TGF-β is secreted extracellulary in latent complexes, it remains unclear whether the local TGF-β expression actually drives
Yuhui Ouyang, Masanori Miyata, Kyosuke Hatsushika, Yuko Ohnuma, Ryohei Katoh, Hideoki Ogawa, Ko Okumura, Keisuke Masuyama, Atsuhito Nakao   +8 more
doaj   +1 more source