Herpes Simplex Virus Type 1 Infection Facilitates Invasion of Staphylococcus aureus into the Nasal Mucosa and Nasal Polyp Tissue [PDF]
PLoS ONE, 2012 BACKGROUND: Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of severe chronic airway disease, such as nasal polyps. However the mechanisms underlying the initiation of damage and/or invasion of the nasal mucosa by S.
Krysko O +2 more
exaly +4 more sources
Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa [PDF]
BMC Microbiology, 2020 Background The host-microbial commensalism can shape the innate immune responses in respiratory mucosa and nasal microbiome also modulates front-line immune mechanism in the nasal mucosa.
Yung Jin Jeon +4 more
doaj +2 more sources
Impairment mechanism of nasal mucosa after radiotherapy for nasopharyngeal carcinoma [PDF]
Frontiers in Oncology, 2022 The nasal mucosa, which performs the crucial functions of filtering, humidifying and temperature regulation, is one of the most vulnerable areas of nasopharyngeal carcinoma (NPC) patients after radiotherapy (RT).
Caishan Fang +11 more
doaj +2 more sources
Rat nasal mucosa‐derived ectodermal mesenchymal stem cells: A new therapeutic option for chronic rhinosinusitis [PDF]
Immunity, Inflammation and DiseaseObjective To investigate the effect of nasal mucosa‐derived ectodermal mesenchymal stem cells (NM‐EMSCs) on the inflammatory state of rats with chronic rhinosinusitis (CRS) and the underlying therapeutic mechanism.
Liujin Li +4 more
doaj +2 more sources
Protocol for optimized nasal mucosa sample processing to obtain high-quality scRNA-seq and scATAC-seq data [PDF]
STAR ProtocolsSummary: Examining nasal mucosa samples is crucial for nasal cavity disease research and diagnosis. Simultaneously obtaining high-quality data for single-cell transcriptomics (single-cell RNA sequencing [scRNA-seq]) and epigenomics (single-cell assay for
Yaling Huang +11 more
doaj +2 more sources
Eosinophils in nasal polyps and nasal mucosa: an immunohistochemical study
Journal of Allergy and Clinical Immunology, 1993 Immunohistochemical staining was performed at the time of endoscopic sinus surgery (ESS), after 6 months, and after 1 year on nasal polyps and biopsy specimens of the macroscopically unaffected mucosa of the middle and inferior turbinate bones of 46 ...
Stoop, A. E. +3 more
core +3 more sources
Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]
, 2003 The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Dufès, Christine +5 more
core +4 more sources
Upregulation of the Vitamin D Receptor in the Nasal Mucosa of Patients With Allergic Rhinitis [PDF]
Journal of Rhinology, 2021 Background and Objectives Vitamin D modulates immunity, including that of allergic diseases, and plays its roles through contact with vitamin D receptors (VDR).
Hyeon Geun Kim +6 more
doaj +1 more source
Effects of adenoid and nasal pathologies in pediatric epistaxis
Acta Medica Alanya, 2022 Aim: The aim of this study was to investigate the effects of adenoid and nasal pathologies in paediatric patients with recurrent epistaxis.Methods: A total of 100 (61 boys, 39 girls) individuals aged 2–17 years (mean age: 8.9 ± 3.6 years) were included ...
Oğuzhan Dikici, Osman Durgut
doaj +1 more source
Asymmetric expression level of clock genes in left vs. right nasal mucosa in humans with and without allergies and in rats: Circadian characteristics and possible contribution to nasal cycle. [PDF]
PLoS ONE, 2018 Numerous peripheral tissues possess self-sustaining daily biologic rhythms that are regulated at the molecular level by clock genes such as PER1, PER2, CLOCK, and BMAL1.
Ha Kyun Kim +4 more
doaj +1 more source