Results 11 to 20 of about 83,352 (300)

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Staphylococcus aureus (S. aureus) plays an important role in the pathogenesis of severe chronic airway disease, such as nasal polyps. However the mechanisms underlying the initiation of damage and/or invasion of the nasal mucosa by S.
XiangDong Wang   +9 more
doaj   +3 more sources

Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range

open access: yesScientific Reports, 2021
Previous studies focusing on the age disparity in COVID-19 severity have suggested that younger individuals mount a more robust innate immune response in the nasal mucosa after infection with SARS-CoV-2.
Konner Winkley   +7 more
doaj   +1 more source

VASOACTIVE SUBSTANCES IN THE NASAL MUCOSA [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1958
Besides histamine another smooth muscle stimulating substance has been found in the nasal mucosa of dog and sheep. It is an acid which is readily oxidized by neutral aqueous potassium permanganate and osmium tetroxide, and is thermostable at pH 10·8 but not at pH 2·8.
C C, TOH, A, MOHIUDDIN
openaire   +2 more sources

Glycolytic reprogramming is involved in tissue remodeling on chronic rhinosinusitis

open access: yesPLoS ONE, 2023
Background Glycolytic reprogramming is a key feature of chronic inflammatory disease. Extracellular matrix (ECM) produced by myofibroblasts plays an important role in tissue remodeling of nasal mucosa in chronic rhinosinusitis (CRS).
Min-Sik Jo   +4 more
doaj   +2 more sources

Microcirculation in the nasal mucosa.

open access: yesFolia Pharmacologica Japonica, 1999
The nasal mucosa has important physiological roles, including the removal of foreign bodies and the warming and humidification of inspired air. The microcirculation in the nasal mucosa facilitates the above processes and plays a role in the periodic swelling and shrinking of the nasal mucosa.
H, Watanabe, H, Tsuru
openaire   +4 more sources

Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]

open access: yes, 2001
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht   +7 more
core   +1 more source

Characteristics of nasal-associated lymphoid tissue (NALT) and nasal absorption capacity in chicken. [PDF]

open access: yesPLoS ONE, 2013
As the main mucosal immune inductive site of nasal cavity, nasal-associated lymphoid tissue (NALT) plays an important role in both antigen recognition and immune activation after intranasal immunization.
Haihong Kang   +3 more
doaj   +1 more source

Development of a nasal mucosa-removal model for evaluating cell therapy

open access: yesRegenerative Therapy, 2021
Introduction: Endoscopic sinus surgery is an effective surgical procedure for treating chronic sinusitis; however, extensive exposure of the bone in the nasal cavity can result in permanent disability postoperatively.
Shun Kikuchi   +5 more
doaj   +1 more source

Transmucosal nasal drug delivery : systemic bioavailability of nasally applied midazolam [PDF]

open access: yes, 2008
Transmucosal nasal drug delivery is a drug delivery option for challenging clinical situations where common drug administrations (e.g., intravenous, intramuscular, or oral) are inapplicable.
Suter-Zimmermann, Katja
core   +1 more source

A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model

open access: yesBiomolecules, 2019
Airway hyperresponsiveness (AHR) has been proposed as a feature of pathogenesis of eosinophilic upper airway inflammation such as allergic rhinitis (AR). The measurement system for upper AHR (UAHR) in rodents is poorly developed, although measurements of
Dan Van Bui   +16 more
doaj   +1 more source

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