Results 81 to 90 of about 1,027,501 (383)
Life, 2023 Skeletal muscle atrophy occurs rapidly as a result of inactivity. Although there are many reports on changes in gene expression during the early phase of muscle atrophy, the patterns of up-and downregulated gene expression after long-term and ...
Shoko Sawano +6 more
doaj +1 more source
Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals
Nature Communications, 2020 A unique property of skeletal muscle is its ability to adapt its mass to changes in activity. Inactivity, as in disuse or aging, causes atrophy, the loss of muscle mass and strength, leading to physical incapacity and poor quality of life.
J. Segalés +12 more
semanticscholar +1 more source
Unimpaired Neuropsychological Performance and Enhanced Memory Recall in Patients with Sbma: A Large Sample Comparative Study. [PDF]
, 2018 Peculiar cognitive profile of patients with SBMA has been described by fragmented literature. Our retrospective study reports the neuropsychological evaluations of a large cohort of patients in order to contribute towards the understanding of this field.
A. (2018)., +10 more
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FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]
, 2019 IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F +24 more
core +2 more sources
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Assessing China’s Situation and Challenges [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2019 This article intends to assess China’s situation and challenges in the context of its deteriorating external and domestic environments. It focuses on the regime-maintenance initiatives of the Party regime and the prospects for political stability in ...
Joseph Yu-shek Cheng
doaj
Hippocampus in health and disease: An overview
Annals of Indian Academy of Neurology, 2012 Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli.
Kuljeet Singh Anand, Vikas Dhikav
doaj +1 more source
A case report of Parry Romberg Syndrome initially presenting as periodontitis [PDF]
, 2018 Parry Romberg Syndrome (PRS) is a rare disorder of progressive hemifacial atrophy, involving soft tissues, fat and occasionally bone. It can co-exist with presentations of Morphea.
Bramley +14 more
core +1 more source