Results 101 to 110 of about 114,786 (336)

Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons [PDF]

, 2006
Basal forebrain (BF) neurons provide the principal cholinergic drive to the hippocampus and cortex. Their degeneration is associated with the cognitive defects of Alzheimer's disease. Immunohistochemical studies suggest that some of these neurons contain
Abogadie, FC, Allen, TGJ, Brown, DA
core   +1 more source

Breathing and balance: Clinical insights and management strategies of respiratory acid‐base disorders

Nutrition in Clinical Practice, EarlyView.
Abstract Respiratory acidosis and alkalosis are two of the four main acid‐base processes encountered in clinical practice. These two processes are tightly balanced by breathing. Identification and management of respiratory acid‐base disorders are important for clinicians, particularly when caring for patients with underlying pulmonary and neurological ...
Anne M. Tucker, Tami N. Johnson
wiley   +1 more source

Protective Effects of the Ketogenic Diet on Cognitive Impairment Induced by Status Epilepticus in Rats: Modulation of Neuroinflammation Through the NF‐κB Signaling Pathway

Pediatric Discovery, EarlyView.
Ketogenic diet has therapeutic effects on neurocircuitry damage and cognitive impairment due to status epilepticus in rats by modulating the NF‐κB signaling pathway. ABSTRACT Epilepsy is a chronic neurological disorder characterized by abnormal synchronized neuronal discharges, leading to cognitive dysfunction. The ketogenic diet (KD) has shown promise
Wandi Wang, Lingman Wang, Chunxue Jiang, Shengxuan Zhang, Chen Tan, Liqiong Peng, Ran Ding, Bing Tian, Xiaojie Song, Li Jiang   +9 more
wiley   +1 more source

Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes [PDF]

, 2018
The realisation of the therapeutic potential of targeting the M1 muscarinic acetylcholine receptor (M1 mAChR) for the treatment of cognitive decline in Alzheimer's disease has prompted the discovery of M1 mAChR ligands showing efficacy in alleviating ...
Bradley, Sophie J., Broad, Lisa M., Brooke, Simon M., Bundgaard, Christoffer, Christopoulos, Arthur, Crabtree, Michael D., Dwomoh, Louis, Felder, Christian C., Langmead, Christopher J., Mogg, Adrian J., Molloy, Colin, Sanger, Helen E., Sexton, Patrick M., Thompson, Karen J., Tobin, Andrew B.   +14 more
core   +1 more source

Microbiota diversity and differences in the respiratory tract of children with pneumonia

Pediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge, Lingyun Hou, Jintao Guo, Xuejing Lv, Yungang Yang   +4 more
wiley   +1 more source

Physical, chemical, and microbiological stability study of diluted atropine eye drops

Journal of Pharmaceutical Health Care and Sciences, 2019
Background Atropine eye drops are indicated for juvenile myopia progression, cycloplegia, amblyopia, and strabismus. According to the package insert, 10 mg/mL atropine eye drops must be diluted for pediatric patients to prevent systemic adverse effects ...
Jumpei Saito, Hitomi Imaizumi, Akimasa Yamatani   +2 more
doaj   +1 more source

Atropine Challenge Test in Screening the Organophosphorus Poisoning Cases with Atypical Presentation; a Brief Report

Archives of Academic Emergency Medicine, 2019
Introduction: Atropine is not recommended in organophosphorus (OPs) poisoning cases without any obvious clinical signs. This study aimed to evaluate the clinical utility of Atropine challenge test in screening OPs poisoning cases with atypical ...
Shahin Shadnia, Nasim Zamani, Sara Nikpour, Ali Saffaei, Mohammad Reza Farnia   +4 more
doaj   +1 more source

Semiochemical applications for managing the grey field slug (Deroceras reticulatum Müller), a major pest of arable crops

Pest Management Science, EarlyView.
Trends in semiochemical research highlight promising attractants and repellents for ‘push–pull’ pest control strategies of the grey field slug. Extracts from plants, predators, entomopathogenic fungi, and essential oils demonstrate potential in modifying grey field slug behaviour, inducing avoidance, antifeeding responses, or mortality, offering ...
Suleiman Mustapha, E Joel Loveridge, Tariq M Butt, Jozsef Vuts, Patricia A Ortega‐Ramos, Samantha M Cook   +5 more
wiley   +1 more source

ANALOGUES OF ATROPINE AND HOMATROPINE. [PDF]

Journal of the American Chemical Society, 1918
n ...
openaire   +3 more sources

Effects of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation: A Multicenter, Randomized Controlled Study

United European Gastroenterology Journal, EarlyView.
ABSTRACT Objective The objective of this study was to investigate the efficacy of transcutaneous auricular vagal nerve stimulation (taVNS) in adult patients with chronic constipation. Design Consecutive patients who met the Rome IV criteria for chronic constipation were enrolled and randomly assigned to either the taVNS group or the sham‐taVNS group ...
Tangyi Liu, Zeyu Wang, Yunling Li, Xiaoyu Kang, Xiangping Wang, Gui Ren, Yong Lv, Jing Li, Yaling Liu, Shuhui Liang, Xin Wang, Xiaojun Huang, Xiaoyin Zhang, Jun Wang, Yongzhan Nie, Hui Luo, Jinbo Sun, Wei Qin, Ying Han, Yanglin Pan   +19 more
wiley   +1 more source