Results 91 to 100 of about 64,436 (205)

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Atropine [PDF]

Heart, 1991
openaire   +2 more sources

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Reconstruction of deep and perforating corneal defects in dogs—A review (Part III/III): The use of corneal sutures and reporting of ocular discomfort

Veterinary Ophthalmology, Volume 28, Issue 2, Page 543-552, March 2025.
Abstract The surgical reconstruction of severe corneal disease is a common and crucial component of the clinical practice of veterinary ophthalmology. The first part of the present review described procedures that utilize autogenous ocular tissues, homologous donor tissues, and heterologous donor tissues in dogs, while the second part reviewed the use ...
R. F. Sanchez
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Repolarization adaptation to rapid change in heart rate in human models – a review

The Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt, Karl‐Jonas Axelsson, Pia Dahlberg, Farzad Vahedi, Gunilla Lundahl, Lennart Gransberg   +5 more
wiley   +1 more source

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier, Elliott J. Jenkins, Andrew Douglas, Jack Talbot, Alexandra Williams, Jonathan Moore, Craig D. Steinback, Liam D. Corr, Zoe H. Adams, Fabio Giuseppe Laginestra, Markus Amann, Philip N. Ainslie, Travis D. Gibbons, Mike Stembridge   +13 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

The role of atropine in myopia control: insights into choroidal and scleral mechanisms

Frontiers in Pharmacology
In this study, we investigate the inhibitory effects of atropine on the progression of experimental myopia by targeting the functions of the choroid and sclera and exploring its potential therapeutic mechanisms.
Longxiang Huang, Longxiang Huang, Longxiang Huang, Longxiang Huang, Jingjin Zhang, Jingjin Zhang, Jingjin Zhang, Jingjin Zhang, Youfang Luo   +8 more
doaj   +1 more source

Chemoenzymatic Synthesis of Chiral Piperidines Using the Immobilized Transaminase ATA‐117 in Continuous Flow Reactors

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza, Ilaria Magrini Alunno, Stefania Patti, Morena Pirotta, Francesca Annunziata, Raffaella Gandolfi, Paola Conti, Chiara Borsari, Ivan Bassanini, Erica Elisa Ferrandi, Daniela Monti, Lucia Tamborini   +11 more
wiley   +1 more source