Results 71 to 80 of about 105,430 (244)

Vagolytic atropine attenuates cerebral vasodilation response during acute orthostatic hypotension [PDF]

open access: yesKorean Journal of Anesthesiology, 2015
BackgroundAtropine is an anticholinergic drug which is commonly used in clinical practice. The effect of parasympathetic block with atropine on dynamic cerebrovascular regulation remains unclear.
Woo-Jong Choi   +5 more
doaj   +1 more source

Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol

open access: yesArtificial Organs, EarlyView.
This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari   +8 more
wiley   +1 more source

Effect of Methoxime Combined with Anticholinergic, Anticonvulsant or Anti-HCN Drugs in Tabun-Poisoned Mice

open access: yesActa Medica, 2003
The effect of methoxime combined with a) atropine, b) benactyzine, c) atropine and natrium thiosulphate, d) atropine and diazepam on antidotal treatment effectiveness was studied in tabun-poisoned mice.
Lucie Ševelová, Josef Vachek
doaj   +1 more source

Stepwise low concentration atropine for myopic control: a 10-year cohort study

open access: yesScientific Reports, 2021
The aim of this study was to analyze changes in refraction and evaluate the variables in school children who received atropine as myopic control for 10 years.
Meng-Ni Chuang   +2 more
doaj   +1 more source

Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]

open access: yes, 1994
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Risk factors for rapid axial length elongation with low concentration atropine for myopia control

open access: yesScientific Reports, 2021
Three hundred and twenty-eight myopic children, randomized to use either 0.01% (N = 166) or 0.02% (N = 162) atropine were enrolled in this study. Gender, age, body mass index(BMI), parental myopia status, atropine concentration used, pupil diameter ...
Aicun Fu   +8 more
doaj   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau   +9 more
wiley   +1 more source

Efficacy of 1% atropine eye drops in retarding progressive axial myopia in Indian eyes

open access: yesIndian Journal of Ophthalmology, 2017
Purpose: The aim of this study is to assess the efficacy of 1% atropine eye drops for the retardation of progressive axial myopia in Indian eyes. Methods: This prospective interventional cohort study included children aged 5–16 years.
Mihir Kothari, Vivek Rathod
doaj   +1 more source

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